High-speed X-ray video demonstrates significant skin movement errors with standard optical kinematics during rat locomotion.
High-speed X-ray video demonstrates significant skin movement errors with standard optical kinematics during rat locomotion.
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DOI：
10.1016/j.jneumeth.2009.10.017
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发表时间：
2010-01-30
影响因子：
3
通讯作者：
Chang, Young-Hui
中科院分区：
文献类型：
--
作者：
Bauman, Jay M.;Chang, Young-Hui
目前啮齿类动物损伤和疾病模型的复杂性超过了最常用的行为分析。本研究的第一个目的是使用高速x射线视频测量大鼠的运动，以建立大鼠后肢运动学的准确基线。第二个目标是通过同时记录和比较来自皮肤标记和直接可视化骨骼标记的后肢运动学来量化由于皮肤运动伪影引起的运动学误差。与x射线数据相比，基于皮肤运动学的关节角度计算产生的误差在膝关节处高达39°，在髋部与脚爪接触处高达31°。通过踝关节和髋部皮肤标记对膝关节位置进行三角测量，提供了更接近（尽管仍然不准确）的骨源性x射线运动学近似。我们发现软组织运动错误是多种因素的结果，其中最令人印象深刻的是肢体的整体姿势。跑步机速度对运动学误差的影响微乎其微。这些发现说明了啮齿动物运动学中皮肤运动误差的意义和背景。
The sophistication of current rodent injury and disease models outpaces that of the most commonly used behavioral assays. The first objective of this study was to measure rat locomotion using high-speed x-ray video to establish an accurate baseline for rat hindlimb kinematics. The second objective was to quantify the kinematics errors due to skin movement artefacts by simultaneously recording and comparing hindlimb kinematics derived from skin markers and from direct visualization of skeletal landmarks. Joint angle calculations from skin-derived kinematics yielded errors as high as 39° in the knee and 31° in the hip around paw contact with respect to the x-ray data. Triangulation of knee position from the ankle and hip skin markers provided closer, albeit still inaccurate, approximations of bone-derived, x-ray kinematics. We found that soft tissue movement errors are the result of multiple factors, the most impressive of which is overall limb posture. Treadmill speed had surprisingly little effect on kinematics errors. These findings illustrate the significance and context of skin movement error in rodent kinematics.
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DOI：
10.1115/1.1933949
发表时间：
2005-08-01
影响因子：
1.7
作者：
Fregly, BJ;Rahman, HA;Banks, SA
通讯作者：
Banks, SA
影响因子：
2.8
作者：
Chang, Young-Hui;Auyang, Arick G.;Nichols, T. Richard
通讯作者：
Nichols, T. Richard
影响因子：
1.8
作者：
Cappozzo, A;Catani, F;DellaCroce, U
通讯作者：
DellaCroce, U
DOI：
10.1078/0944-2006-00015
发表时间：
2001-01-01
期刊：
ZOOLOGY-ANALYSIS OF COMPLEX SYSTEMS
影响因子：
--
作者：
Druzisky, KA;Brainerd, EL
通讯作者：
Brainerd, EL
影响因子：
3.8
作者：
Banks, SA;Fregly, BJ;Romagnoli, S
通讯作者：
Romagnoli, S