POSTNATAL DEVELOPMENT OF BETA-GLUCURONIDASE IN JEJINUM AND ILEUM OF RATS
POSTNATAL DEVELOPMENT OF BETA-GLUCURONIDASE IN JEJINUM AND ILEUM OF RATS
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DOI：
10.1139/o65-024
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发表时间：
1965-01-01
期刊：
影响因子：
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通讯作者：
KOLDOVSKY, O
中科院分区：
文献类型：
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作者：
HERINGOVA, A;JIRSOVA, V;KOLDOVSKY, O
在大鼠出生后第4天到第17天之间，小肠粘膜匀浆中的β-葡萄糖醛酸酶活性在远端肠中比在近端三分之一中更高。近端活性下降到第 20 天，而远端活性从出生到第 15 天上升，然后快速下降到第 20 天 (20X)。从第 20 天开始，近端和远端的活动相同。 β-葡萄糖醛酸酶（以每三分之一小肠的总活性变化表示）在出生后发育过程中近端部分的变化非常小；最大的变化发生在远端部分。第 15 天进行的肾上腺切除术抑制了第 19 天远端部分活动的正常减少。
[beta]-Glucuronidase activity in the homogenates of the mucosa of the small intestine is higher in the distal than in the proximal third of the intestine between the 4th and 17th postnatal day in rats. Activity falls proximally up to day 20, while distally, activity rises from birth up to day 15 and then falls rapidly up to day 20 (20X). Starting from day 20, activity is the same proximally and distally. [beta]-Glucuronidase (expressed as changes of total activity per third of the small intestine) changes during the post-natal development very little in the proximal part; the greatest changes occur in the distal part. Adrenalectomy, performed on day 15, inhibits the normal decrease in activity seen in the distal part on day 19.