Assessment of interstitial water content of articular cartilage with T1 relaxation
Assessment of interstitial water content of articular cartilage with T1 relaxation
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DOI：
10.1016/j.mri.2008.09.005
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发表时间：
2009-06-01
影响因子：
2.5
通讯作者：
Nieminen, Miika T.
中科院分区：
文献类型：
--
作者：
Berberat, Jatta E.;Nissi, Mikko J.;Nieminen, Miika T.
在关节软骨退变的早期，间质水分含量明显增加。此前，7松弛与水分含量有关，但已知它强烈地受胶原取向的影响。取牛(N=20)的髌骨、股骨和胫骨的关节软骨塞，在9.4T定位于T-1和T-2，以测试T-1松弛反映软骨水分含量的能力。作为参考，测定了水分和蛋白多糖(PG)含量。显著(P
The interstitial water content typically increases in the early degeneration of articular cartilage. Previously, 7 relaxation has been related to water content, yet it is known to be strongly affected by the collagen orientation. Articular cartilage plugs from the bovine patella, femur and tibia (N=20) were mapped for T-1 and T-2 at 9.4 T to test the ability of T-1 relaxation to reflect cartilage water content. As a reference, water and proteoglycan (PG) contents were determined. Significant (P