Fluorogenic bidirectional displacement probebased real-time isothermal DNA amplification and specific visual detection of products

Fluorogenic bidirectional displacement probebased real-time isothermal DNA amplification and specific visual detection of products
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DOI:
10.1039/c6cc05158h
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发表时间:
2016-01-01
影响因子:
4.9
通讯作者:
Mu, Ying
Mu, Ying
中科院分区:
化学2区
文献类型:
--
作者:
Ding, Xiong;Wang, Guoping;Mu, Ying

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设计了一种独特的荧光核酸探针,称为荧光双向位移探针,它既可以作为引物,又可以作为扩增产物的信号指示剂,用于开发高灵敏度和高特异性的实时恒温DNA扩增及其产物的可视化检测。
A unique fluorogenic nucleic acid probe has been devised, called the fluorogenic bidirectional displacement probe, which can serve as both the primer and the signal indicator of amplification products for the development of the real-time isothermal DNA amplification and its visual detection of products with high sensitivity and specificity.