EVIDENCE FOR CIGARETTE-SMOKING AS A MAJOR RISK FACTOR FOR PERIODONTITIS
EVIDENCE FOR CIGARETTE-SMOKING AS A MAJOR RISK FACTOR FOR PERIODONTITIS
复制标题
DOI：
10.1902/jop.1993.64.1.16
复制
发表时间：
1993-01-01
影响因子：
4.3
通讯作者：
KENT, RL
中科院分区：
文献类型：
--
作者：
HABER, J;WATTLES, J;KENT, RL
在糖尿病和非糖尿病研究组中分别评估了吸烟作为牙周炎危险因素的作用。获得了胰岛素依赖型糖尿病 (IDDM) 受试者和非糖尿病受试者的按年龄（19 至 40 岁）和性别分层的受试者列表。对于 IDDM 组 (n = 132) 和非糖尿病组 (n = 95)，通过从每个受试者列表中随机选择受试者来构建年龄和性别分层样本。通过电话招募患者、进行检查并获取他们的医疗和牙科病史。在非糖尿病受试者中，19至30岁组（46%对12%）和31至40岁组（88%对33%），当前吸烟者的牙周炎患病率明显高于从不吸烟者（P小于或等于0.005）。在 19 至 30 岁（8.2% 与 3.4%）和 31 至 40 岁（14.3% 与 4.3%）年龄组中，当前吸烟者中牙龈袋深度大于或等于 4 毫米部位的受试者平均百分比高于从不吸烟者 (P = 0.001)。吸烟对 IDDM 受试者的影响与在非糖尿病人群中观察到的相似。当前吸烟者和从不吸烟者之间的菌斑阳性部位比例没有差异。患病率数据的归因风险百分比表明，在非糖尿病受试者中，很大一部分（19 至 30 岁组中高达 51% 的牙周炎和 31 至 40 岁组中 32% 的牙周炎）与吸烟有关。这些发现表明吸烟者是牙周炎的高危人群，并且吸烟可能是牙周炎最重要的环境危险因素。
THE ROLE OF SMOKING as a risk factor for periodontitis was assessed separately in diabetic and nondiabetic study groups. Subject listings stratified for age (19 to 40 years) and sex were obtained for subjects with insulin-dependent diabetes mellitus (IDDM) and nondiabetic subjects. For both the IDDM group (n = 132) and the nondiabetic group (n = 95), age and sex stratified samples were constructed by random selection of subjects from each subject listing. Patients were recruited by phone, examined, and their medical and dental histories obtained. Among nondiabetic subjects, the prevalence of periodontitis was markedly higher among current smokers compared with never smokers (P less-than-or-equal-to 0.005) in both the 19 to 30 year-old (46% vs. 12%) and 31 to 40 year-old groups (88% vs. 33%). The subject mean percent of sites with gingival pocket depth greater-than-or-equal-to 4 mm was higher among current smokers than never smokers (P = 0.001) in the 19 to 30 (8.2% vs. 3.4%) and 31 to 40 (14.3% vs. 4.3%) age groups. The effects of smoking among IDDM subjects were similar to that observed in the nondiabetic population. There were no differences between current and never smokers in the proportion of sites positive for plaque. Attributable risk percents from prevalence data suggest that among nondiabetic subjects, a large proportion, perhaps as much as 51% of the periodontitis in the 19 to 30 year old group and 32% of the periodontitis in the 31 to 40 year old group, is associated with smoking. These findings suggest that smokers are a high risk group for periodontitis, and that smoking may be the single most important environmental risk factor for periodontitis.