The never-ending story: from pluripotency to plant developmental plasticity.
The never-ending story: from pluripotency to plant developmental plasticity.
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DOI：
10.1242/dev.117614
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发表时间：
2015-07-01
期刊：
影响因子：
--
通讯作者：
Lohmann JU
中科院分区：
文献类型：
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作者：
Gaillochet C;Lohmann JU
植物是固着生物，其中一些可以活上千年。与大多数动物不同，植物采用胚胎后发育模式，由多能干细胞的持续活动驱动。因此，植物能够在很长一段时间内启动新的器官，许多物种可以通过从头器官发生很容易地取代失去的身体结构。经典研究还表明，植物组织具有显著的体外去分化和增殖能力，突出了植物细胞命运具有高度可塑性的事实。这表明调节命运转换的机制必须在大多数植物细胞中持续活跃，并且细胞多能性的控制是多种发育程序的核心。在这里，我们回顾了多能性是如何在植物干细胞系统中建立的，它是如何在发育和生长过程中保持并在再生过程中重新启动的，以及这些机制最终如何有助于植物惊人的发育可塑性。总结：这篇综述讨论了多能性是如何在植物干细胞系统中建立的，它是如何在发育和生长过程中保持的，以及它是如何在再生过程中重新启动的。
Plants are sessile organisms, some of which can live for over a thousand years. Unlike most animals, plants employ a post-embryonic mode of development driven by the continuous activity of pluripotent stem cells. Consequently, plants are able to initiate new organs over extended periods of time, and many species can readily replace lost body structures by de novo organogenesis. Classical studies have also shown that plant tissues have a remarkable capacity to undergo de-differentiation and proliferation in vitro, highlighting the fact that plant cell fate is highly plastic. This suggests that the mechanisms regulating fate transitions must be continuously active in most plant cells and that the control of cellular pluripotency lies at the core of diverse developmental programs. Here, we review how pluripotency is established in plant stem cell systems, how it is maintained during development and growth and re-initiated during regeneration, and how these mechanisms eventually contribute to the amazing developmental plasticity of plants. Summary: This Review discusses how pluripotency is established in plant stem cell systems, how it is maintained during development and growth, and how it is re-initiated during regeneration.