Mesial temporal sclerosis: Diagnosis with fluid-attenuated inversion-recovery versus spin-echo MR imaging
Mesial temporal sclerosis: Diagnosis with fluid-attenuated inversion-recovery versus spin-echo MR imaging
复制标题
DOI：
10.1148/radiology.199.2.8668780
复制
发表时间：
1996-05-01
期刊：
影响因子：
19.7
通讯作者：
Riederer, SJ
中科院分区：
文献类型：
--
作者：
Jack, CR;Rydberg, CH;Riederer, SJ
目得：比较液体衰减反转恢复（FLAIR）序列的准确性与传统的双自旋回波（SE）序列在识别增加的信号强度的海马在内侧颞叶硬化症（MTS）的准确性。材料和方法：三个盲审查独立分级的FLAIR和SE图像在36例难治性复杂部分性癫痫发作。测试了生殖能力。结果：FLAIR图像的准确率为97%，SE图像为91%（P <0.02）。放射科医生更喜欢FLAIR的对比度属性，而不是SE图像的对比度属性（P < .0001）。手术与非手术海马对比噪声比（C/N）测量结果显示SE序列的第二回波优于FLAIR序列（P <0.002）。结论：FLAIR序列可提供T2加权像，完全抑制脑脊液高信号。建议将FLAIR序列纳入癫痫患者的常规MR评估中。
PURPOSE: To compare the accuracy of a fluid-attenuated inversion-recovery (FLAIR) sequence with that of a conventional double spin-echo (SE) sequence in the identification of increased signal intensity of the hippocampus in mesial temporal sclerosis (MTS).MATERIALS AND METHODS: Three blinded reviewers independently graded the FLAIR and SE images in 36 patients with intractable complex partial seizures. Reproducibility was tested. At histopathologic examination, the criterion standard, 32 patients had MTS.RESULTS: The accuracy of FLAIR images was 97% versus 91% for SE images (P < .02). The radiologists preferred the contrast properties of FLAIR to those of SE images by a significant margin (P < .0001). Surgical to nonsurgical hippocampal contrast-to-noise ratio (C/N) measurements were better for the second echo of the SE sequence than for FLAIR (P < .002). Hippocampus-to-background tissue C/N was superior with FLAIR (P < .0001).CONCLUSION: FLAIR provides images with T2-weighted contrast and complete suppression of high signal intensity of CSF. Incorporation of a FLAIR sequence into the routine MR evaluation of patients with epilepsy is recommended.