Are you laughing at me? Neural correlates of social intent attribution to auditory and visual laughter
Are you laughing at me? Neural correlates of social intent attribution to auditory and visual laughter
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DOI：
10.1002/hbm.24806
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发表时间：
2019-10-22
影响因子：
4.8
通讯作者：
Wildgruber, Dirk
中科院分区：
文献类型：
--
作者：
Ethofer, Thomas;Stegmaier, Sophia;Wildgruber, Dirk
笑是一种多方面的信号，它可以传达促进社会联系的社会接受，也可以传达造成社会痛苦的社会拒绝。在当前的研究中，我们在功能磁共振成像研究中解决了社交意图归因于听觉或视觉笑声的神经相关性，以识别显示活动与社交意图评级呈线性增加的大脑区域。负面社交意图归因与内侧前额叶皮层/前扣带皮层 (mPFC/ACC) 内的激活增加相关。有趣的是，在该区域内，听觉笑声的负面社会意图归因比视觉笑声更多地表现在嘴侧。我们的研究结果证实了 mPFC/ACC 作为处理具有不同模态特定子区域的“社会疼痛”关键节点的作用。其他显示出激活增加的大脑区域包括用于视觉呈现笑声的双侧额下回和右上/颞中回（STG/MTG）和用于听觉呈现笑声的双侧 STG，且各模式之间没有重叠。同样，积极的社交意图归因与右顶叶下叶和右额中回的血流动力学反应有关，但视觉和听觉笑声的活动没有重叠。我们的研究结果表明，听觉和视觉笑声的社交意图归因于相邻但空间上不同的神经结构。
Laughter is a multifaceted signal, which can convey social acceptance facilitating social bonding as well as social rejection inflicting social pain. In the current study, we addressed the neural correlates of social intent attribution to auditory or visual laughter within an fMRI study to identify brain areas showing linear increases of activation with social intent ratings. Negative social intent attributions were associated with activation increases within the medial prefrontal cortex/anterior cingulate cortex (mPFC/ACC). Interestingly, negative social intent attributions of auditory laughter were represented more rostral than visual laughter within this area. Our findings corroborate the role of the mPFC/ACC as key node for processing "social pain" with distinct modality-specific subregions. Other brain areas that showed an increase of activation included bilateral inferior frontal gyrus and right superior/middle temporal gyrus (STG/MTG) for visually presented laughter and bilateral STG for auditory presented laughter with no overlap across modalities. Similarly, positive social intent attributions were linked to hemodynamic responses within the right inferior parietal lobe and right middle frontal gyrus, but there was no overlap of activity for visual and auditory laughter. Our findings demonstrate that social intent attribution to auditory and visual laughter is located in neighboring, but spatially distinct neural structures.