Recovery of resistance (R) factors from a drug-free community.

Recovery of resistance (R) factors from a drug-free community.
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从无毒品社区恢复耐药(R)因子。

DOI:
10.1016/s0140-6736(69)90482-6
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发表时间:
1969
期刊:
The Lancet
影响因子:
--
通讯作者:
R. Moellering
R. Moellering
中科院分区:
--
文献类型:
--
作者:
P. Gardner;D. Smith;H. Beer;R. Moellering

文献摘要

被引文献

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对所罗门群岛的一个未使用抗生素人群的研究表明,在自然条件下,R因子可以在低频率下恢复,而不需要抗菌药物的选择力。这些R因子从土壤和粪便标本中回收,介导对链霉素和四环素的抗性,并且像在美国回收的某些R因子一样,通过磷酸化使链霉素失活。
A study of an antibiotic virgin population in the Solomon Islands showed that R factors can be recovered at low frequency under natural conditions without the selective force of antimicrobial drugs. These R factors were recovered from soil and stool specimens, mediated resistance to streptomycin and tetracycline, and, like certain R factors recovered in the United States, inactivated streptomycin by phosphorylation.