Mercury contamination in spotted seatrout, Cynoscion nebulosus: An assessment of liver, kidney, blood, and nervous system health
Mercury contamination in spotted seatrout, Cynoscion nebulosus: An assessment of liver, kidney, blood, and nervous system health
复制标题
DOI：
10.1016/j.scitotenv.2010.08.019
复制
发表时间：
2010-11-01
影响因子：
9.8
通讯作者：
Jensen, Asger L.
中科院分区：
文献类型：
--
作者：
Adams, Douglas H.;Sonne, Christian;Jensen, Asger L.
南佛罗里达（佛罗里达礁岛-佛罗里达湾-大沼泽地地区）的海鱼在其组织中积累的汞（Hg）浓度高于美国东南部其他地区的类似鱼类，尽管尚不清楚这些升高的水平是否会影响鱼类的健康。在本研究中，我们使用可量化的病理和生化指标来探索来自汞污染高的南佛罗里达和来自佛罗里达州印第安河泻湖的海鱼的汞相关差异。作为参考区域，来自南佛罗里达的成熟斑海参（Cynoscion nebulosus）的所有组织中汞的浓度都明显高于来自印第安河泻湖的组织，并且在观察汞暴露影响的研究的阈值范围内。汞在两个区域的组织分布趋势相同，肾脏组织中浓度最高，其次是肝脏、肌肉、大脑、性腺、血浆生化显示，铁、无机磷酸盐、乳酸脱氢酶和天冬氨酸转氨酶的浓度在南佛罗里达显著较低。此外，果糖胺和碱性磷酸酶在南佛罗里达显著较低。肝脏组织学显示，固缩/坏死、间质性炎症和胆管增生仅在南佛罗里达的seatrout中发现。在Indian River Lagoon的肾组织中，经常发现脂肪变性/糖原。肝细胞骨架和形态学的变化可能解释了研究区域之间血液参数的一些差异。神经化学分析表明，脑n -甲基- d -天冬氨酸（NMDA）受体(但不包括毒菌碱胆碱能受体、单胺氧化酶、这些发现提供了令人信服的证据，表明汞含量升高可能导致可量化的病理和生化变化，从而可能影响斑鲈的健康，也可能影响其他海洋鱼类(C) 2010 Elsevier B V All rights reserved
Marine fishes in South Florida (Florida Keys-Florida Bay-Everglades region) accumulate higher concentrations of mercury (Hg) in their tissues than similar fishes from other areas of the southeastern US, though it is not known whether these elevated levels affect fish health In this study, we used quantifiable pathological and biochemical indicators to explore Hg-associated differences in marine fish from South Florida, where Hg contamination is high, and from Indian River Lagoon, Florida, which served as a reference area Hg concentrations us all tissues of mature spotted seatrout (Cynoscion nebulosus) from South Florida were significantly higher than those from Indian River Lagoon and were within the threshold range of those in studies where effects of Hg exposure have been observed The distribution of Hg among tissues followed the same trend in both areas, with the greatest concentration in kidney tissue, followed by liver, muscle, brain, gonad, and red blood cells Blood-plasma biochemistry showed that concentrations of iron, inorganic phosphate, lactate dehydrogenase, and aspartate aminotransferase were significantly less in South Florida Also, fructosamine and alkaline phosphatase were significantly less in South Florida liver histology revealed that pyknosis/necrosis, interstitial inflammation, and bile duct hyperplasia were found only in seatrout from South Florida, and steatosis/glycogen was mole frequently found in Indian River Lagoon specimens In renal tissue, interstitial inflammation, glomerular dilatation and thickening, and tubular degeneration and necrosis were more frequently found in South Florida specimens Changes in the liver cytoskeleton and morphology may explain some of the differences us blood parameters between study areas Neurochemical analyses showed that brain N-methyl-D-aspartic acid (NMDA) receptors (but not those of muscarinic cholinergic receptors, monoamine oxidase, or acetylcholinesterase) were significantly less in fish from South Florida than from Indian River Lagoon These findings provide compelling evidence that elevated Hg could cause quantifiable pathological and biochemical changes that might influence the health of spotted seatrout and could also affect other marine fish species (C) 2010 Elsevier B V All rights reserved