Factors Associated with Self-reported Medication Adherence in Japanese Community-dwelling Elderly Individuals: The Nakajima Study
Factors Associated with Self-reported Medication Adherence in Japanese Community-dwelling Elderly Individuals: The Nakajima Study
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DOI：
10.1248/yakushi.20-00254
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发表时间：
2021-01-01
影响因子：
0.3
通讯作者：
Yamada, Masahito
中科院分区：
文献类型：
--
作者：
Ishida, Natsuko;Tokumoto, Yurina;Yamada, Masahito
老年人的药物不依从性是一个主要问题，使他们无法获得最佳的治疗效果。确定影响药物依从性的因素对于改善和维持老年人口的健康以及提高医疗保健经济至关重要。本研究的目的是检查自我报告的药物依从性的患病率，并确定相关因素和健康相关的生活质量（HRQOL）的影响，在日本社区居住的老年人口。这项横断面研究是Nakajima研究的一部分，针对的是老年居民。2017年接受健康检查的60岁。通过访谈和自我管理的问卷调查获得有关药物依从性的数据。使用视觉模拟量表评估药物依从性，并使用EuroQol五维问卷（3个级别）评估HRQOL。在455名参与者中，低和高药物依从性分别见于9.7%和66.2%的参与者（视觉模拟评分< 80%和<100%）。95%）。服用药物的参与者的药物依从性明显较低。比那些每天服用一次或两次药物的人每天服用三次;涉及药物管理的方案。每天3次的药物依从性明显较低。使用药物简介手册和HRQOL与药物依从性呈显著正相关。我们的研究结果表明，低给药频率和使用药物简介书与老年人的药物依从性呈正相关，这反过来又可以提高他们的生活质量。
Medication non-adherence in the elderly population is a major problem, preventing them from obtaining optimal therapeutic effects. Identifying the factors affecting medication adherence is crucial for improving and maintaining health among the elderly population and enhance healthcare economy. The purpose of this study was to examine the prevalence of self-reported medication adherence, and identify the associated factors and the influence of health-related quality of life (HRQOL) in the Japanese community-dwelling elderly population. This cross-sectional study was part of the Nakajima study and targeted inhabitants aged. 60 years who underwent health examinations in 2017. Data regarding medication adherence were acquired through interviews and self-administered questionnaires. Medication adherence were assessed using a visual analog scale, and HRQOL was assessed by EuroQol five-dimensional questionnaire with 3 levels. Among the 455 participants, low and high medication adherence were seen in 9.7% and 66.2% of the participants, respectively (visual analog scores < 80% and. 95%, respectively). Medication adherence was significantly lower in participants taking medications. 3 times daily than in those taking medications once or twice daily; a regimen involving drug administration. 3 times daily had significantly lower odds of medication adherence. The use of a drug profile book and HRQOL had significant positive association with medication adherence. Our results suggest that low dosing frequency and using a drug profile book was positively associated with medication adherence among elderly persons, which in turn could enhance their QOL.