Registration of 3-D CT and 2-D flat images of mouse via affine transformation.
Registration of 3-D CT and 2-D flat images of mouse via affine transformation.
复制标题
通过仿射变换配准小鼠的 3-D CT 和 2-D 平面图像。
DOI：
10.1109/titb.2007.904631
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发表时间：
2008
期刊：
影响因子：
--
通讯作者：
Wong,StephenTC
中科院分区：
文献类型：
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作者：
Xia,Zheng;Huang,Xishi;Zhou,Xiaobo;Sun,Youxian;Ntziachristos,Vasilis;Wong,StephenTC
将最大直径只有几毫米的小鼠小肿瘤的3-D荧光分子断层扫描（FMT）图像与跨度约10厘米的整个动物的更大的CT图像直接共注册是困难的。本文首先提出了一种二维平面和三维CT图像的配准新方法，以方便小三维FMT图像与大三维CT图像的配准。提出了一种结合差分进化和改进单纯形法的二维平面CT图像与三维CT图像配准算法，并用模拟图像和真实小鼠图像进行了验证。通过二维配准实现三维FMT与CT图像对齐的可视化显示了良好的效果。
It is difficult to directly coregister the 3-D fluorescence molecular tomography (FMT) image of a small tumor in a mouse whose maximal diameter is only a few millimeters with a larger CT image of the entire animal that spans about 10 cm. This paper proposes a new method to register 2-D flat and 3-D CT image first to facilitate the registration between small 3-D FMT images and large 3-D CT images. A novel algorithm combining differential evolution and improved simplex method for the registration between the 2-D flat and 3-D CT images is introduced and validated with simulated images and real images of mice. The visualization of the alignment of the 3-D FMT and CT image through 2-D registration shows promising results.