CT CHARACTERISTICS OF PRIMARY HEPATIC MASS LESIONS IN DOGS
CT CHARACTERISTICS OF PRIMARY HEPATIC MASS LESIONS IN DOGS
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DOI：
10.1111/j.1740-8261.2011.01917.x
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发表时间：
2012-05-01
影响因子：
1.7
通讯作者：
Tsujimoto, Hajime
中科院分区：
文献类型：
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作者：
Fukushima, Kenjiro;Kanemoto, Hideyuki;Tsujimoto, Hajime
关于犬肝脏肿瘤的CT影像表现与病理诊断之间的关系的信息很少。我们的目的是阐明犬肝肿瘤的CT表现特征。从病历中总结了33只狗的资料，其中肝细胞癌14只，肝细胞腺瘤14只，结节状增生5只。对每一种组织学诊断的CT表现进行表征和统计分析。肝细胞癌的常见表现包括动脉期中央强化(79%，P=0.0030)和边缘强化(93%，P=0.00043)，囊样病变(93%)，包膜形成(93%)，门脉低密度(86%)和平衡期(93%)。肝腺瘤在动脉期呈典型的弥漫性强化(57%，P=0.013)，结节状增生(60%)也有此表现，而肝细胞癌则无此表现。结节状增生较少有包膜结构(20%，P=0.0087)。结节状增生的肿块体积明显小于肝细胞癌和肝腺瘤(P分别为0.0033和0.038)。肝腺瘤在动脉期和门脉期的高密度影(即对比剂滞留)明显高于其他组(P分别为0.037和0.037)。结节增生在平衡期等密度较多(P=0.043)。(C)2012年兽医放射与超声。
Little information is available on the relationship between computed tomography (CT) imaging findings and the pathologic diagnosis of canine hepatic tumors. Our purpose was to clarify the characteristic features of CT findings in liver tumors in dogs. Data from 33 dogs with either a hepatocellular carcinoma, n = 14, hepatocellular adenoma, n = 14, or nodular hyperplasia, n = 5 were summarized from medical records. CT features for each histologic diagnosis were characterized and analyzed statistically. Common findings in hepatocellular carcinoma included central (79%, P = 0.0030) and marginal enhancement (93%, P = 0.00043) in the arterial phase, cyst-like lesions (93%), capsule formation (93%), and hypoattenuation in the portal (86%), and equilibrium phases (93%). Hepatic adenoma was characterized by a characteristic diffuse enhancement pattern during the arterial phase (57%, P = 0.013), which was also found in nodular hyperplasia (60%), but never in hepatocellular carcinoma. Nodular hyperplasia was less likely to have a capsule structure (20%, P = 0.0087). Mass size was significantly smaller in nodular hyperplasia than in hepatocellular carcinoma and hepatic adenoma (P = 0.0033 and 0.038, respectively). Hyperattenuation in the arterial and the portal phase i.e. contrast retention, was more frequent in hepatic adenoma than in the other groups (P = 0.037 and 0.037, respectively). Nodular hyperplasia was more frequently isoattenuating in the equilibrium phase (P = 0.043). (C) 2012 Veterinary Radiology & Ultrasound.