Four new bioactive bromophenols from the palauan Sponge Phyllospongia dendyi
Four new bioactive bromophenols from the palauan Sponge Phyllospongia dendyi
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DOI：
10.1046/j.1444-2906.2001.00339.x
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发表时间：
2001-10-01
影响因子：
1.9
通讯作者：
Shizuri, Y
中科院分区：
文献类型：
--
作者：
Hattori, T;Konno, A;Shizuri, Y
从帕劳海绵中分离得到四种新的溴苯酚和一种已知的溴苯酚衍生物。利用核磁共振和质谱学数据确定了这些新化合物的结构。它们具有抗巨藻活性，IC50值为0.02-0.05p.p.m。此外，所有化合物在下午0.5-5.0的浓度下对不同种类的藻类都有抗微藻作用。
Four new bromophenols and a known bromophenol derivative have been isolated from the Palauan sponge Phyllospongia dendyi. The structures of these new compounds were established using nuclear magnetic resonance and mass spectral data. They showed antimacroalgal activity with IC50 values of 0.02-0.05 p.p.m. Moreover, all compounds were antimicroalgal against various classes of algae at concentrations of 0.5-5.0 p.p.m.