Effectiveness of adjunctive hyaluronic acid application in coronally advanced flap in Miller class I single gingival recession sites: a randomized controlled clinical trial
Effectiveness of adjunctive hyaluronic acid application in coronally advanced flap in Miller class I single gingival recession sites: a randomized controlled clinical trial
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DOI：
10.1007/s00784-018-2537-4
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发表时间：
2019-03-01
影响因子：
3.4
通讯作者：
Rojas, Mariana A.
中科院分区：
文献类型：
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作者：
Pilloni, Andrea;Schmidlin, Patrick R.;Rojas, Mariana A.
ObjectiveTheirrandomizedcontrolledclinicaltrial的目的是评估连续性透明质酸（HA）应用于冠状动脉推进皮瓣（CAF）手术在单一米勒I类/退缩1型（RT 1）牙龈退缩treatment.Material and Methods 30例患者一次退缩入组; 15例随机分配CAF + HA和15例单独CAF。18个月后计算后退减少（RecRed）、临床附着水平增加（CAL-增益）、探诊袋深度（PPD）和角化组织宽度（KT）的变化、完全牙根覆盖（CRC）和平均牙根覆盖（MRC）。术后发病率（疼痛强度，不适，肿胀）记录7天后，使用视觉模拟量表（VAS）。结果18个月后，RecRed是统计学显着高于试验组（2.7毫米[1.0]）比对照组（1.9毫米[1.0]; p=0.007）。发现两组的PPD轻微但具有统计学显著性增加。两种处理之间KT增加无统计学显著差异。试验部位的CRC为80%，对照部位为33.3%（p
ObjectivesThe aim of this randomized controlled clinical trial was to evaluate the possible advantages of adjunctive hyaluronic acid (HA) application in thecoronally advanced flap (CAF) procedure in single Miller class I/recession type 1 (RT1) gingival recession treatment.Material and methodsThirty patients with one recession were enrolled; 15 were randomly assigned CAF + HA and 15 to CAF alone. The recession reduction (RecRed), clinical attachment level gain (CAL-gain), changes in probing pocket depth (PPD) and in the width of keratinized tissue (KT), complete root coverage (CRC), and mean root coverage (MRC) were calculated after 18months. Post-operative morbidity (pain intensity, discomfort, and swelling) was recorded 7days after treatment using visual analogue scale (VAS).ResultsAfter 18months, RecRed was statistically significantly higher in the test group (2.7mm [1.0]) than in the control group (1.9mm [1.0]; p=0.007). PPD were found to be slightly but statistically significantly increased in both groups. No statistically significant difference was found for KT gain between treatments. CRC was 80% for test and 33.3% for control sites (p