Surveillance of spontaneous abortions. Power in environmental monitoring.
Surveillance of spontaneous abortions. Power in environmental monitoring.
复制标题
自然流产的监测。
DOI：
10.1093/oxfordjournals.aje.a112475
复制
发表时间：
1977
影响因子：
5
通讯作者：
D. Warburton
中科院分区：
文献类型：
--
作者：
J. Kline;Z. Stein;B. Strobino;M. Susser;D. Warburton
In this paper we aim to demonstrate the advantage of using spontaneous abortions to keep a watch on teratogens in the environment. The proposed system depends on monitoring both the incidence of spontaneous abortions and the prevalence of defects in the conceptus in spontaneous abortions. A surveillance system based on spontaneous abortions rather than on birth defects has four important advantages. First, lead time is gained for the discovery of the effects of teratogenic exposure. A change in the incidence of spontaneous abortions or of anomalies in spontaneous abortions could in theory be detected six months or more before a change in the incidence of birth defects. Second, abortion specimens, unlike liveborn infants, can be studied at will and preserved for future studies as well. Third, many anomalies that appear among spontaneous abortions appear never or rarely among
