Mechanical Characterization of Porcine Corneas
Mechanical Characterization of Porcine Corneas
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DOI：
10.1115/1.4006089
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发表时间：
2012-03-01
影响因子：
1.7
通讯作者：
Pandolfi, A.
中科院分区：
文献类型：
--
作者：
Boschetti, F.;Triacca, V.;Pandolfi, A.
为了研究猪角膜的力学行为，进行了一项实验计划。我们报告了在51只新鲜猪眼上进行的全角膜充气试验和离体角膜条单轴试验的结果。对从先前充盈的角膜上切下的样本进行了单轴测试。角膜行为的特征在于通过弹性刚度，在平均压力顶点位移和平均单轴应力-应变曲线上测量;以及通过横向收缩系数，峰值应力和单轴应力-应变曲线上测量的破坏应力。在切除的条带上进行的单轴测试允许测量角膜硬度的各向异性，并将角膜的硬度与巩膜的硬度进行比较。通过对离体角膜条的单轴松弛曲线，获得了角膜的粘性特性。测量了有关的几何参数，并借助于弹性薄壳理论，从平均充气试验数据导出了应力-应变曲线，并与文献中的类似数据进行了比较。该实验系统已开发的猪和人类角膜的机械测试的未来应用。[DOI 10.1115/1.4006089]
An experimental program has been carried out in order to investigate the mechanical behavior of porcine corneas. We report the results of inflation tests on the whole cornea and uniaxial tests on excised corneal strips, performed on 51 fresh porcine eyes. Uniaxial tests have been performed on specimens cut from previously inflated corneas. The cornea behavior is characterized by means of elastic stiffness, measured on both average pressure-apex displacement and average uniaxial stress-strain curves; and by means of transversal contraction coefficient, peak stress, and failure stress measured on uniaxial stress-strain curves. Uniaxial tests performed on excised strips allowed to measure the anisotropy in the corneal stiffness and to compare the stiffness of the cornea with the one of the sclera. Viscous properties of the cornea have been obtained through uniaxial relaxation curves on excised corneal strips. The relevant geometrical parameters have been measured and, with the aid of the elastic thin shell theory, a stress-strain curve has been derived from the average inflation test data and compared with similar data available in the literature. The experimental system has been developed in view of future applications to the mechanical testing of both porcine and human corneas. [DOI: 10.1115/1.4006089]