Hypoxia-inducible haemoglobins of Daphnia pulex and their role in the response to acute and chronic temperature increase.

Hypoxia-inducible haemoglobins of Daphnia pulex and their role in the response to acute and chronic temperature increase.
复制标题

水蚤缺氧诱导的血红蛋白及其在急慢性温度升高反应中的作用

DOI:
10.1016/j.bbapap.2013.01.036
复制
发表时间:
2013
期刊:
Biochimica et biophysica acta
影响因子:
--
通讯作者:
Paul RJ
Paul RJ
中科院分区:
--
文献类型:
--
作者:
Zeis B;Becker D;Gerke P;Koch M;Paul RJ

文献摘要

参考文献

被引文献

相似文献

在其栖息地严重的氧气和温度变化的挑战蚤pulexis。为了应对缺氧,设备的氧转运蛋白的数量和质量调整的差异表达血红蛋白亚型。本研究使用转录组学和蛋白质组学方法关注20 °C驯化动物对高温的反应。急性温度应激(30 °C)诱导的低氧诱导型Hb亚型最强烈,导致血红蛋白mRNA库在8 h内增加70%。长期适应适度升高的温度(24 °C)仅引起Hb mRNA套件的微小变化。然而,血红蛋白的血淋巴池的浓度升高了80%。在这种情况下,组成型Hb同种型显示出最强的增加,其中Hb01和Hb02占呼吸蛋白总量的64%。急性温度应激后的调节模式可能反映了温度诱导的组织缺氧,而在持续暴露于适度升高的温度的情况下,适应过程使氧稳态成功恢复。这篇文章是题为“氧结合和传感蛋白”的特刊的一部分。
Daphnia pulexis challenged by severe oxygen and temperature changes in its habitat. In response to hypoxia, the equipment of oxygen transport proteins is adjusted in quantity and quality by differential expression of haemoglobin isoforms. This study focuses on the response of 20 °C acclimated animals to elevated temperature using transcriptomic and proteomic approaches. Acute temperature stress (30 °C) induced the hypoxia-inducible Hb isoforms most strongly, resulting in an increase of the haemoglobin mRNA pool by 70% within 8 h. Long-term-acclimation to moderately elevated temperature (24 °C) only evoked minor changes of the Hb mRNA suite. Nevertheless, the concentration of the hemolymph pool of haemoglobin was elevated by 80%. In this case, the constitutive Hb isoforms showed the strongest increase, with Hb01 and Hb02 contributing by 64% to the total amount of respiratory protein. The regulation patterns upon acute temperature stress likely reflect temperature-induced tissue hypoxia, whereas in case of persisting exposure to moderately elevated temperature, acclimation processes enabled the successful return to oxygen homeostasis. This article is part of a Special Issue entitled: Oxygen Binding and Sensing Proteins.
DOI: 10.1074/jbc.274.15.10649
发表时间: 1999-04-09
影响因子: 4.8
作者:
Kimura, S;Tokishita, S;Yamagata, H
通讯作者: Yamagata, H
溞血红蛋白的珠蛋白组成与无脊椎动物血红蛋白氨基酸组成的比较
DOI: --
发表时间: 1990
期刊:
影响因子: --
作者:
K. Peeters;J. Mertens;P. Hébert;L. Moens
通讯作者: L. Moens
用于高通量基因组研究的双标记表达微阵列方案
DOI: 10.2506/cgbtr-201102
发表时间: 2011
期刊: Cgb Technical Report
影响因子: --
作者:
J. A. Lopez;J. Colbourne
通讯作者: J. Colbourne
DOI: 10.1152/physiolgenomics.00179.2002
发表时间: 2003-06-24
影响因子: 4.6
作者:
Treinin, M;Shliar, J;Horowitz, M
通讯作者: Horowitz, M
DOI: --
发表时间: 1982
期刊:
影响因子: --
作者:
Michiyori Kobayashi;T. Hoshi
通讯作者: T. Hoshi