A Symbol Digit Modalities Test version suitable for functional MRI studies

A Symbol Digit Modalities Test version suitable for functional MRI studies
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DOI:
10.1016/j.neulet.2009.03.081
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发表时间:
2009-05-29
影响因子:
2.5
通讯作者:
Avila, Cesar
Avila, Cesar
中科院分区:
医学4区
文献类型:
--
作者:
Forn, Cristina;Belloch, Vicente;Avila, Cesar

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符号数字模态测试是一项简单的测试,用于评估多种神经系统疾病(如多发性硬化症)的认知障碍。我们改编了该认知任务的口头版本,使其适合功能性磁共振成像研究。符号数字模式测试表现与涉及选择性注意力和工作记忆功能的额叶和顶叶区域的大脑活动增加有关。这些可能为未来评估多发性硬化症患者和其他临床人群潜在异常皮质激活的研究提供基础。由爱思唯尔爱尔兰有限公司出版
The Symbol Digit Modalities Test is an easy test used to assess cognitive impairment in a wide range of neurological diseases, like multiple sclerosis. We adapted the oral version of this cognitive task making it suitable for functional Magnetic Resonance Imaging studies. Symbol Digit Modalities Test performance was associated with increased brain activity in frontal and parietal areas involved in selective attention and working memory functions. These may provide the basis for future studies assessing potential abnormal cortical activations in multiple sclerosis patients and other clinical populations. Published by Elsevier Ireland Ltd.