EXPERIMENTAL MOSQUITO-TRANSMISSION OF PLASMODIUM KNOWLESI TO MAN AND MONKEY
EXPERIMENTAL MOSQUITO-TRANSMISSION OF PLASMODIUM KNOWLESI TO MAN AND MONKEY
复制标题
DOI：
10.4269/ajtmh.1968.17.355
复制
发表时间：
1968-01-01
影响因子：
3.3
通讯作者：
ALPERT, E
中科院分区：
文献类型：
--
作者：
CHIN, W;CONTACOS, PG;ALPERT, E
诺氏疟原虫H株通过巴拉巴克按蚊的叮咬在猴与人之间、人与人之间以及人与猴之间传播。所有试图通过被感染蚊子叮咬来感染人类的尝试都是成功的，一名志愿者在仅仅一次感染性叮咬后就感染了病毒。人的未闭期为9 ~ 12天，猴为6天。感染表现出周期性，其特点是相对较高的寄生虫血症和中度至重度的临床表现。这种人畜共患病的意义，因为它可能会影响消灭疟疾的计划进行了讨论。
The H strain of P. knowlesi was transmitted through the bites of Anopheles balabacencis balabacensis mosquitoes from monkey to man, from man to man, and from man back to monkey. All attempts to infect man through the bites of infected mosquitoes were successful, one volunteer contracting infection after only a single infective bite. The prepatent periods in man ranged from 9 to 12 days, and in the monkey was 6 days. The infections exhibited a quotidian periodicity, and were characterized by relatively high parasitemia and moderate to severe clinical manifestations. The significance of this zoonosis as it may affect a program of malaria eradication is discussed.