The dissipation and transport of veterinary antibiotics in a sandy loam soil
The dissipation and transport of veterinary antibiotics in a sandy loam soil
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DOI：
10.1016/j.chemosphere.2006.09.095
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发表时间：
2007-02-01
期刊：
影响因子：
8.8
通讯作者：
Boxall, Alistair B. A.
中科院分区：
文献类型：
--
作者：
Blackwell, Paul A.;Kay, Paul;Boxall, Alistair B. A.
研究了磺胺氯哒嗪和土霉素在桑迪壤土中的环境归趋。用这些化合物强化液体猪粪，然后施入土壤小区，研究田间条件下的淋溶、消散和地表径流。此外，由于大环内酯类抗生素泰乐菌素已给予来源于浆液的猪，因此也在采集的样品中进行了分析。磺胺氯哒嗪消散迅速，DT 50和DT 90值分别为3.5天和18.9天，但土霉素的持久性更强，DT 50和DT 90值分别为21.7天和98.3天。处理后20天，在地表径流样品中检测到磺胺氯哒嗪和土霉素，最高浓度分别为25.9和0.9微克/升，但在40厘米深的土壤水样品中仅检测到磺胺氯哒嗪，最高浓度为0.78微克/升。泰乐菌素在所有土壤或水样中均未检出。结果表明，泰乐菌素在泥浆中施用时，在土壤中积累或污染地下水或地表水的风险很小。然而，如果用于治疗牧场上的动物，泰乐菌素可能会造成风险，并且不能排除在浆料储存期间形成的泰乐菌素转化产物产生的风险。土霉素对地下水或地表水造成污染的风险极低，但有可能在土壤中持久存在，磺胺氯哒嗪对地下水或地表水造成污染的风险中等，但在土壤中积累的可能性较低。这些发现与化合物的吸附和持久性特征一致，并支持一些大规模的监测研究，这些研究测量了环境中的这些抗生素类。(c)2006爱思唯尔有限公司保留所有权利。
The environmental fate of the antibiotics sulfachloropyridazine and oxytetracycline was investigated in a sandy loam soil. Liquid pig manure was fortified with the compounds and then applied to soil plots to investigate leaching, dissipation and surface run-off under field conditions. Additionally, as the macrolide antibiotic tylosin had been administered to the pigs from which the slurry had been sourced, this was also analysed for in the samples collected. Sulfachloropyridazine dissipated rapidly with DT50 and DT90 values of 3.5 and 18.9 days but oxytetracycline was more persistent with DT50 and DT90 values of 21.7 and 98.3 days. Both sulfachloropyridazine and oxytetracyline were detected in surface run-off samples at maximum concentrations of 25.9 and 0.9 mu g/l respectively but only sulfachloropyridazine was detected in soil water samples at a maximum concentration of 0.78 mu g/l at 40 cm depth 20 days after treatment. Tylosin was Dot detected in any soil or water samples. The results indicated that tylosin, when applied in slurry, posed very little risk of accumulating in soil or contaminating ground or surface water. However, tylosin may pose a risk if used to treat animals on pasture and risks arising from transformation products of tylosin, formed during slurry storage, cannot be ruled out. Oxytetracycline posed a very low risk of ground or surface water contamination but had the potential to persist in soils and sulfachloropyridazine posed a moderate risk of contaminating ground or surface water but had low potential to accumulate in soils. These findings were consistent with the sorption and persistence characteristics of the compounds and support a number of broad-scale monitoring studies that have measured these antibiotic classes in the environment. (c) 2006 Elsevier Ltd. All rights reserved.