INTERMOLECULAR INTERACTIONS IN COLLAGEN SELF-ASSEMBLY AS REVEALED BY FOURIER-TRANSFORM INFRARED-SPECTROSCOPY
INTERMOLECULAR INTERACTIONS IN COLLAGEN SELF-ASSEMBLY AS REVEALED BY FOURIER-TRANSFORM INFRARED-SPECTROSCOPY
复制标题
DOI：
10.1126/science.6857249
复制
发表时间：
1983-01-01
期刊：
影响因子：
56.9
通讯作者：
VEIS, A
中科院分区：
文献类型：
--
作者：
JAKOBSEN, RJ;BROWN, LL;VEIS, A
当[鼠]胶原蛋白分子的溶液在中性pH和中等离子强度下从4-30度加热时。C，一个自发的自组装过程，在这个过程中产生了原生型胶原纤维。通过傅立叶变换红外光谱技术，可以在水介质中实时监测热诱导纤维形成过程中发生的事件。对观测到的谱带进行了初步的指认。
When a solution of [rat] collagen molecules, at neutral pH and moderate ionic strength, is warmed from 4-30.degree. C, a spontaneous self-assembly process takes place in which native-type collagen fibers are produced. Events occurring during thermally induced fibrillogenesis process can be monitored, in aqueous media and in real time, by Fourier transform infrared spectroscopic techniques. Tentative assignments of observed spectral bands are given.