National and regional estimates of term and preterm babies born small for gestational age in 138 low-income and middle-income countries in 2010.
National and regional estimates of term and preterm babies born small for gestational age in 138 low-income and middle-income countries in 2010.
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DOI：
10.1016/s2214-109x(13)70006-8
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发表时间：
2013-07
影响因子：
34.3
通讯作者：
Black, Robert E.
中科院分区：
文献类型：
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作者：
Lee, Anne C. C.;Katz, Joanne;Blencowe, Hannah;Cousens, Simon;Kozuki, Naoko;Vogel, Joshua P.;Adair, Linda;Baqui, Abdullah H.;Bhutta, Zulfiqar A.;Caulfield, Laura E.;Christian, Parul;Clarke, Sian E.;Ezzati, Majid;Fawzi, Wafaie;Gonzalez, Rogelio;Huybregts, Lieven;Kariuki, Simon;Kolsteren, Patrick;Lusingu, John;Marchant, Tanya;Merialdi, Mario;Mongkolchati, Aroonsri;Mullany, Luke C.;Ndirangu, James;Newell, Marie-Louise;Nien, Jyh Kae;Osrin, David;Roberfroid, Dominique;Rosen, Heather E.;Sania, Ayesha;Silveira, Mariangela F.;Tielsch, James;Vaidya, Anjana;Willey, Barbara A.;Lawn, Joy E.;Black, Robert E.
关于出生时小于胎龄婴儿的数量和早产合并症的国家估计数字无法获得。我们的目的是估计2010年138个低收入和中等收入国家中足月和早产儿的胎龄小于（足月- sga和早产儿- sga）的患病率及其与低出生体重（<2500 g）的关系。小于胎龄的定义是1991年美国国家参考人口的胎儿生长低于10%。来自22个出生队列研究（14个低收入和中等收入国家）和世卫组织孕产妇和围产期健康全球调查（23个国家）的数据被用来模拟早产出生的流行率。通过荟萃分析计算sga早产儿的患病率。2010年，低收入和中等收入国家估计有3240万婴儿出生时小于胎龄（占活产婴儿的27%），其中1060万婴儿出生时足月和低出生体重。足月sga婴儿的患病率从东亚的5.3%到南亚的41.5%不等，而早产sga婴儿的患病率从北非的1.2%到东南亚的3.0%不等。在1800万低出生体重婴儿中，59%为足月低出生体重婴儿，41%为早产儿。三分之二的小胎龄婴儿出生在亚洲（南亚为1740万）。在低收入和中等收入国家，sga早产婴儿总数为280万。大多数小于胎龄的婴儿出生在印度、巴基斯坦、尼日利亚和孟加拉国。在低收入和中等收入国家，小于胎龄分娩的负担非常高，并集中在南亚。为出生过小或过早的婴儿实施有效干预措施是提高存活率和减少残疾、发育迟缓和非传染性疾病的紧急优先事项。比尔和梅林达·盖茨基金会向儿童基金会美国基金提供赠款，以支持儿童健康流行病学参考小组的活动。
National estimates for the numbers of babies born small for gestational age and the comorbidity with preterm birth are unavailable. We aimed to estimate the prevalence of term and preterm babies born small for gestational age (term-SGA and preterm-SGA), and the relation to low birthweight (<2500 g), in 138 countries of low and middle income in 2010. Small for gestational age was defined as lower than the 10th centile for fetal growth from the 1991 US national reference population. Data from 22 birth cohort studies (14 low-income and middle-income countries) and from the WHO Global Survey on Maternal and Perinatal Health (23 countries) were used to model the prevalence of term-SGA births. Prevalence of preterm-SGA infants was calculated from meta-analyses. In 2010, an estimated 32·4 million infants were born small for gestational age in low-income and middle-income countries (27% of livebirths), of whom 10·6 million infants were born at term and low birthweight. The prevalence of term-SGA babies ranged from 5·3% of livebirths in east Asia to 41·5% in south Asia, and the prevalence of preterm-SGA infants ranged from 1·2% in north Africa to 3·0% in southeast Asia. Of 18 million low-birthweight babies, 59% were term-SGA and 41% were preterm. Two-thirds of small-for-gestational-age infants were born in Asia (17·4 million in south Asia). Preterm-SGA babies totalled 2·8 million births in low-income and middle-income countries. Most small-for-gestational-age infants were born in India, Pakistan, Nigeria, and Bangladesh. The burden of small-for-gestational-age births is very high in countries of low and middle income and is concentrated in south Asia. Implementation of effective interventions for babies born too small or too soon is an urgent priority to increase survival and reduce disability, stunting, and non-communicable diseases. Bill & Melinda Gates Foundation by a grant to the US Fund for UNICEF to support the activities of the Child Health Epidemiology Reference Group (CHERG).