Walking and leisure-time activity and risk of hip fracture in postmenopausal women
Walking and leisure-time activity and risk of hip fracture in postmenopausal women
复制标题
DOI：
10.1001/jama.288.18.2300
复制
发表时间：
2002-11-13
影响因子：
120.7
通讯作者：
Colditz, G
中科院分区：
文献类型：
--
作者：
Feskanich, D;Willett, W;Colditz, G
背景体育活动可以降低老年妇女髋部骨折的风险，尽管所需的活动类型和持续时间尚未确定。散步是老年人中最常见的活动，有证据表明，它可以增加股骨骨密度，降低骨折风险。目的评估绝经后妇女散步，休闲时间活动和髋部骨折风险的关系。设计，设置，前瞻性分析始于1986年，对美国11个州的注册护士进行了为期12年的随访。共有61200名绝经后妇女（年龄40-77岁，98%白色），基线时未诊断出癌症、心脏病、中风或骨质疏松症。主要结果测量由轻度或中度创伤引起的髋部骨折事件，通过休闲活动的强度和持续时间以及步行、坐和站立的时间进行分析，结果从1986年至1998年，415例髋部骨折事件被确定。在比例风险模型中控制了年龄、体重指数、绝经后激素的使用、吸烟和饮食摄入后，髋部骨折的风险降低了6%（95%置信区间[CI]，4%-9%; P
Context Physical activity can reduce the risk of hip fractures in older women, although the required type and duration of activity have not been determined. Walking is the most common activity among older adults, and evidence suggests that it can increase femoral bone density and reduce fracture risk.Objective To assess the relationship of walking, leisure-time activity, and risk of hip fracture among postmenopausal women.Design, Setting, and Participants Prospective analysis begun in 1986 with 12 years of follow-up in the Nurses' Health Study cohort of registered nurses within 11 US states. A total of 61200 postmenopausal women (aged 40-77 years and 98% white) without diagnosis of cancer, heart disease, stroke, or osteoporosis at baseline.Main Outcome Measures Incident hip fracture resulting from low or moderate trauma, analyzed by intensity and duration of leisure-time activity and by time spent walking, sitting, and standing, measured at baseline and updated throughout follow-up.Results From 1986 to 1998, 415 incident hip fracture cases were identified. After controlling for age, body mass index, use of postmenopausal hormones, smoking, and dietary intakes in proportional hazards models, risk of hip fracture was lowered by 6% (95% confidence interval [CI], 4%-9%; P