The B-Matrix Must Be Rotated When Correcting for Subject Motion in DTI Data
The B-Matrix Must Be Rotated When Correcting for Subject Motion in DTI Data
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DOI：
10.1002/mrm.21890
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发表时间：
2009-06-01
影响因子：
3.3
通讯作者：
Jones, Derek K.
中科院分区：
文献类型：
--
作者：
Leemans, Alexander;Jones, Derek K.
为了可靠地估计扩散张量MRI（DTI）测量，诸如分数各向异性和纤维取向，需要大量的扩散编码图像，优选地心脏门控以减少脉动伪影。然而，伴随的较长采集时间增加了受试者运动对这些测量的估计产生不利影响的机会。虽然校正运动伪影可以提高DTI的准确性，但在重新排列图像时经常被忽视的步骤是重新定向B矩阵，以便正确保留方向信息。据我们所知，大多数研究小组和软件包目前省略了这一重新定位步骤。考虑到最近DTI应用的激增，包括例如神经外科规划（其中错误可能具有严重后果），重要的是调查忽略执行B矩阵重定向的影响。在这项工作中，一个系统的研究，调查的影响，忽略了重新定向的B矩阵的DTI数据在运动校正。扩散纤维束成像的后果进行了讨论。Magn Reson Med 61：1336-1349，2009. (C)2009威利-利斯公司
To estimate diffusion tensor MRI (DTI) measures, such as fractional anisotropy and fiber orientation, reliably, a large number of diffusion-encoded images is needed, preferably cardiac gated to reduce pulsation artifacts. However, the concomitant longer acquisition times increase the chances of subject motion adversely affecting the estimation of these measures. While correcting for motion artifacts improves the accuracy of DTI, an often overlooked step in realigning the images is to reorient the B-matrix so that orientational information is correctly preserved. To the best of our knowledge, most research groups and software packages currently omit this reorientation step. Given the recent explosion of DTI applications including, for example, neurosurgical planning (in which errors can have drastic consequences), it is important to investigate the impact of neglecting to perform the B-matrix reorientation. In this work, a systematic study to investigate the effect of neglecting to reorient the B-matrix on DTI data during motion correction is presented. The consequences for diffusion fiber tractography are also discussed. Magn Reson Med 61:1336-1349, 2009. (C) 2009 Wiley-Liss, Inc.