Does smoking affect intraocular pressure? Findings from the blue mountains eye study
Does smoking affect intraocular pressure? Findings from the blue mountains eye study
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DOI：
10.1097/00061198-200306000-00005
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发表时间：
2003-06-01
影响因子：
2
通讯作者：
Mitchell, P
中科院分区：
文献类型：
--
作者：
Lee, AJ;Rochtchina, E;Mitchell, P
目的：为了评估吸烟和眼内压之间的关系，材料和方法：蓝山眼科研究调查了3654名居民，年龄49岁及以上，在悉尼西部地区，澳大利亚从1992年至1994年。一位受过训练的采访者收集了详细的吸烟史。使用Goldmann压平眼压计测量眼内压;由于右眼和左眼之间的相关性非常高，因此仅提供右眼数据。参加者使用青光眼药物或谁以前的白内障手术的证据excluded.Results：目前吸烟者（15.8%的参与者）有略高的平均眼内压（16.34毫米汞柱）比非吸烟者（16.04毫米汞柱）。在调整年龄和性别后，眼内压（右眼）与当前吸烟显著相关（P = 0.03）。在同时调整与眼内压相关的其他变量（包括血压、糖尿病、近视、青光眼、家族史和假性剥脱（P = 0.02））后，这种相关性保持不变（结论：本研究确定了当前吸烟与眼内压之间的适度横截面正相关性）。
Purpose: To assess the relationship between smoking and intraocular pressure.Materials and Methods: The Blue Mountains Eye Study examined 3654 residents aged 49 years and older in an area west of Sydney, Australia from 1992 to 1994. A trained interviewer collected a detailed history of smoking. Intraocular pressure was measured using Goldmann applanation tonometry; as the correlation between right and left eyes was very high, only right-eye data are presented. Participants using glaucoma medications or who had evidence of previous cataract surgery were excluded.Results: Current smokers (15.8% of participants) had slightly higher mean intraocular pressures (16.34 mm Hg) than nonsmokers (16.04 mm Hg). Intraocular pressure (in the right eye) was significantly associated with current smoking, after adjusting for age and sex (P = 0.03). This association remained unchanged after simultaneous adjustment for other variables associated with intraocular pressure, including blood pressure, diabetes, myopia, glaucoma, family history, and pseudoexfoliation (P = 0.02).Conclusions: This study identified a modest cross-sectional positive association between current smoking and intraocular pressure.