PROTONS AND ANAEROBIOSIS
PROTONS AND ANAEROBIOSIS
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DOI：
10.1126/science.6298937
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发表时间：
1983-01-01
期刊：
影响因子：
56.9
通讯作者：
MOMMSEN, TP
中科院分区：
文献类型：
--
作者：
HOCHACHKA, PW;MOMMSEN, TP
在动物的氧限制期间，葡萄糖可以通过能量效率不同的几种代谢途径发酵，并产生各种终产物（如乳酸盐、丙氨匹碱、章鱼碱、琥珀酸盐或丙酸盐）。由于通过发酵和通过发酵中形成的腺苷三磷酸的水解产生质子的相反pH依赖性，产生的质子的总摩尔数总是每摩尔可发酵底物两个。然而，琥珀酸和丙酸发酵中产生的每摩尔质子分别比乳酸发酵中产生的每摩尔质子多两倍和三倍的腺苷三磷酸。
During oxygen limitation in animals, glucose can be fermented via several metabolic pathways varying in energetic efficiency and leading to various end products (such as lactate, alanopine, octopine, succinate, or propionate). Because of oppositepH dependencies of proton production by fermentation and by hydrolysis of adenosine triphosphate formed in the fermentation, the total number of moles of protons generated is always two per mole of the fermentable substrate. However, two and three times more adenosine triphosphate can be turned over per mole of protons produced in succinate and propionate fermentations, respectively, than in lactate fermentation.