Clinical Development of Liposomal Platinum

Clinical Development of Liposomal Platinum
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铂脂质体的临床开发

DOI:
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发表时间:
1990
期刊:
影响因子:
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通讯作者:
G. Berestein
G. Berestein
中科院分区:
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文献类型:
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作者:
R. P. Soler;A. Khokhar;J. Lautersztain;Salam Al Baker;K. Francis;D. M. Kiger;G. Berestein

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近年来,我们一直致力于开发载体依赖性抗肿瘤药物。这些试剂应具有以下性质:与母体化合物相比增强的抗肿瘤活性、降低的毒性、缺乏交叉抗性以及与药物载体的相容性。
AbstractWe have been interested for several years in the development of carrier-dependent antitumor agents. these agents should have the following properties: enhanced antitumor activity compared with the parent compound, decreased toxicity, lack of cross-resistance, and compatibility with the drug carrier.