Prevalence of dementia in a southern European population in two different time periods:: the ZARADEMP Project
Prevalence of dementia in a southern European population in two different time periods:: the ZARADEMP Project
复制标题
DOI：
10.1111/j.1600-0447.2007.01006.x
复制
发表时间：
2007-10-01
影响因子：
6.7
通讯作者：
Aznar, S.
中科院分区：
文献类型：
--
作者：
Lobo, A.;Saz, P.;Aznar, S.
目的：比较两个不同时间段和两个不同研究的痴呆患病率。方法：对Zaragoza研究或ZARADEMP-0(n=1080)和现在ZARADEMP项目第一波或ZARADEMP-I(n=3715)的具有代表性的65岁老年人随机抽样进行访谈。标准化测量包括老年精神状态和病史和病因学时间表。结果：调整后，全球痴呆患病率无显著差异：ZARADEMP-0为5.2%(95%CI=3.9-6.6)，ZARADEMP-I为3.9%(95%CI=3.3-4.5)(患病率为0.75；95%CI=0.56-1.02)。然而，ZARADEMP-I在男性中的患病率明显较低，特别是在70至84岁的所有年龄组。结论：全球老年人口痴呆症患病率的稳定性已被记录在案。然而，在老年男性中发现的发病率下降刺激了环境假说。
Objective: To compare the prevalence of dementia in two different time periods and two different studies.Method: Representative, random samples of the elderly (> 65 years) in the Zaragoza Study or ZARADEMP-0 (n = 1080) completed the previous decade, and now in Wave I of the ZARADEMP Project or ZARADEMP-I (n = 3715) were interviewed. Standardized measures included the Geriatric Mental State and the History and Aetiology schedule. Cases of dementia were diagnosed according to DSM-IV criteria.Results: Adjusted, global prevalence of dementia has not varied significantly: it was 5.2% (95% CI = 3.9-6.6) in ZARADEMP-0 and 3.9% (95% CI = 3.3-4.5) in ZARADEMP-I (prevalence ratio = 0.75; 95% CI = 0.56-1.02). However, the prevalence in ZARADEMP-I was significantly lower among men, particularly in all age groups between 70 and 84 years.Conclusion: Stability of the global prevalence of dementia in the elderly population has been documented. However, the decreased prevalence found in elderly men stimulated environmental hypotheses.