Cell-Surface Differentiation in the Mouse

Cell-Surface Differentiation in the Mouse
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小鼠细胞表面分化

DOI:
10.1007/978-1-4615-7505-4_12
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发表时间:
1980
影响因子:
4.4
通讯作者:
T. Springer
T. Springer
中科院分区:
医学2区
文献类型:
--
作者:
T. Springer

文献摘要

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分化是一个过程,其中无关细胞产生专门的组织和细胞亚群具有独特的特征。这涉及许多不同基因的协调控制,其中一些基因影响细胞表面分子的表达。那些可以用抗体识别并在一些但不是所有组织上表达的分子被称为分化抗原(Boyse和Old,1969)。在分化抗原的表达中发生定性和定量变化。
Differentiation is the process whereby indifferent cells give rise to specialized tissues and cellular subpopulations with distinctive characteristics. This involves the coordinated control of many different genes, some of which affect the expression of molecules at the cell surface. Those molecules that can be identified with antibodies and are expressed on some but not all tissues are called differentiation antigens (Boyse and Old, 1969). Both qualitative and quantitative variations occur in the expression of differentiation antigens.