The DASH Diet and Insulin Sensitivity
The DASH Diet and Insulin Sensitivity
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DOI：
10.1007/s11906-010-0168-5
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发表时间：
2011-02-01
影响因子：
5.6
通讯作者：
Blumenthal, James A.
中科院分区：
文献类型：
--
作者：
Hinderliter, Alan L.;Babyak, Michael A.;Blumenthal, James A.
生活方式的改变，包括采用饮食方法来阻止高血压（DASH）的饮食模式，超重或肥胖者的体重减轻，以及体力活动，都能有效预防和治疗高血压。健康的生活方式也可能对与高血压相关的代谢异常（如胰岛素抵抗）产生有益的影响。本文综述了DASH饮食和减肥加运动对血压和胰岛素敏感性的独立和综合影响，重点是最近发表的ENCORE研究结果。我们的数据表明，DASH饮食计划单独降低了超重个体的血压，这些超重个体的血压高于最佳血压，但只有当DASH饮食作为更全面的生活方式改变计划（包括运动和减肥）的一部分实施时，才能观察到胰岛素敏感性的显着改善。
Lifestyle modifications, including adoption of the Dietary Approaches to Stop Hypertension (DASH) dietary pattern, weight loss in individuals who are overweight or obese, and physical activity, are effective in the prevention and treatment of hypertension. A healthy lifestyle may also have beneficial effects on metabolic abnormalities, such as insulin resistance, that are associated with high blood pressure. This review examines the independent and combined effects of the DASH diet and weight loss plus exercise on blood pressure and insulin sensitivity, with a focus on recently published results from the ENCORE study. Our data suggest that the DASH eating plan alone lowers blood pressure in overweight individuals with higher than optimal blood pressure, but significant improvements in insulin sensitivity are observed only when the DASH diet is implemented as part of a more comprehensive lifestyle modification program that includes exercise and weight loss.