Total syntheses of lamellarin D and H. The first synthesis of lamellarin-class marine alkaloids
Total syntheses of lamellarin D and H. The first synthesis of lamellarin-class marine alkaloids
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DOI：
10.1016/s0040-4020(97)00287-1
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发表时间：
1997-04-28
期刊：
影响因子：
2.1
通讯作者：
Iwao, M
中科院分区：
文献类型：
--
作者：
Ishibashi, F;Miyazaki, Y;Iwao, M
描述了海洋多芳香族生物碱片藻素D(1)和H(2)的全合成。通过b -基内酯介导的吡咯环形成和已知的苯并异喹啉5、苯甲酸酯6和溴乙酸乙酯的内酯化反应，构建了五环片藻素环体系。1997爱思唯尔科学有限公司
Total syntheses of marine polyaromatic alkaloids, lamellarin D (1) and H (2), are described. The pentacyclic lamellarin ring system was constructed by B-ylide mediated pyrrole ring formation and subsequent lactonization of 4 obtained by an assembly of known benzylisoquinoline 5, benzoate 6 and ethyl bromoacetate. (C) 1997 Elsevier Science Ltd.