Light treatment for nonseasonal depression: speed, efficacy, and combined treatment
Light treatment for nonseasonal depression: speed, efficacy, and combined treatment
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DOI：
10.1016/s0165-0327(98)00005-6
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发表时间：
1998-05-01
影响因子：
6.6
通讯作者：
Kripke, DF
中科院分区：
文献类型：
--
作者：
Kripke, DF
背景：使用强光治疗非季节性的重性抑郁症需要重新评估。研究方法：对非季节性重性抑郁症的光照治疗的临床试验与冬季抑郁症的光照治疗的选定试验和抗抑郁药的临床药物试验进行了比较。结果如下：光治疗非季节性抑郁症产生的净效益在12- 35%的范围内，往往在一周内;结论：光的值为非季节性和季节性抑郁症是可比的。光似乎比精神药理学治疗更快地产生抗抑郁效果。局限性：没有直接随机比较光照和药物治疗非季节性抑郁症的数据。临床相关性：明亮的光线可以与标准疗法结合治疗非季节性抑郁症，并表现出协同作用。(C)1998年Elsevier Science B.V.
Background: Using bright light for treating major depressive disorders which are not seasonal needs reassessment. Methods: Clinical trials of light treatment for nonseasonal major depressive disorders were compared with selected trials of light treatment of winter depression and with antidepressant clinical drug trials. Results: Light treatment of nonseasonal depression produces net benefits in the range of 12-35%, often within I week; Conclusions: Light's value for nonseasonal and seasonal depression are comparable. Light appears to produce faster antidepressant benefits than psychopharmacologic treatment. Limitations: Direct randomizing comparisons between light and medications for nonseasonal depression are not available. Clinical relevance: Bright light can be combined with standard therapies for treating nonseasonal depressions and appears synergistic. (C) 1998 Elsevier Science B.V.