Process, mechanism, and explanation related to externalizing behavior in developmental psychopathology
Process, mechanism, and explanation related to externalizing behavior in developmental psychopathology
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DOI：
10.1023/a:1019808712868
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发表时间：
2002-10-01
影响因子：
3.6
通讯作者：
Hinshaw, SP
中科院分区：
文献类型：
--
作者：
Hinshaw, SP
一方面，概念化和统计建模的进展，以及对交易途径、基因-环境相关性和相互作用以及调节变量和中介变量的增强认识，提高了人们对需要考虑解释精神病理学发展和维持的因素和过程的认识。重点关注注意力问题，冲动和破坏性行为模式，我解决的概念方法的种类最有可能导致在该领域的解释模型的进步。从我自己的研究项目的过程和机制的结果揭示了既有希望和局限性。进展将来自于使用遗传信息设计，变量和以人为中心的研究，明确测试的发展过程，系统的方法来调节和调解，利用“自然实验”，以及预防和干预试验的进行，旨在强调解释以及结果。总而言之，只有转化研究的进步（将基础科学和应用科学联系起来），以及进一步发展交易性的、系统性的解释方法，才能带来突破。
Advances in conceptualization and statistical modeling, on the one hand, and enhanced appreciation of transactional pathways, gene-environment correlations and interactions, and moderator and mediator variables, on the other, have heightened awareness of the need to consider factors and processes that explain the development and maintenance of psychopathology. With a focus on attentional problems, impulsivity, and disruptive behavior patterns, I address the kinds of conceptual approaches most likely to lead to advances regarding explanatory models in the field. Findings from my own research program on processes and mechanisms reveal both promise and limitations. Progress will emanate from use of genetically informative designs, blends of variable and person-centered research, explicit testing of developmental processes, systematic approaches to moderation and mediation, exploitation of "natural experiments," and the conduct of prevention and intervention trials designed to accentuate explanation as well as outcome. In all, breakthroughs will occur only with advances in translational research-linking basic and applied science-and with the further development of transactional, systemic approaches to explanation.