Reproducibility of peroneal motor nerve conduction measurement in older adults
Reproducibility of peroneal motor nerve conduction measurement in older adults
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DOI：
10.1016/j.clinph.2012.07.027
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发表时间：
2013-03-01
影响因子：
4.7
通讯作者：
Strotmeyer, Elsa S.
中科院分区：
文献类型：
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作者：
Ward, Rachel E.;Boudreau, Robert M.;Strotmeyer, Elsa S.
目的：虽然神经病变在老年人中很常见，但神经传导(NC)在老年人中的重复性还没有得到很好的证实。方法：在健康、老龄化和身体成分研究中，我们测量了一组参与者(平均年龄=82.9+/-2.7，n=62，女性50%，黑人51.6%，糖尿病35.5%)的腓骨运动NC幅度和速度。使用变异系数(CVs)、组内相关系数(ICCs)和Bland Altman图，比较同一考生在同一天进行的两组测量结果。结果：低变异系数(2.15~4.24%)和中至高ICCs(0.75~0.99)。没有发现不同指标之间的系统性差异。尽管在一些亚组中人数很少，但我们发现糖尿病、种族或研究地点在重复性方面没有差异。结论：NC测量在老年人中具有中等到高度的观察内重复性，不受糖尿病、种族或性别的影响。意义：这些数据提供了证据，支持在衰老研究中使用这些措施。(C)2012年国际临床神经生理学联合会。爱思唯尔爱尔兰出版公司版权所有。
Objective: While neuropathy is common in the elderly, nerve conduction (NC) reproducibility in older adults is not well-established. We sought to evaluate intraobserver reproducibility of peroneal motor NC measures in a diverse sample of older adults.Methods: We measured peroneal motor NC amplitude and velocity in a subset of participants (mean age = 82.9 +/- 2.7, n = 62, 50% female, 51.6% black, 35.5% DM) in the Health, Aging, and Body Composition Study. Using coefficients of variation (CVs), intraclass correlation coefficients (ICCs), and Bland Altman Plots, we compared two sets of measurements taken by the same examiner hours apart on the same day.Results: Low CVs (2.15-4.24%) and moderate to high ICCs (0.75-0.99) were observed. No systematic variation was found across measures. Despite small numbers in some subgroups, we found no differences in reproducibility by diabetes, race or study site.Conclusion: NC measures have moderate to high intraobsever reproducibility in older adults and are not affected by diabetes, race, or gender. Significance: These data provide evidence to support use of these measures in aging research. (C) 2012 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland All rights reserved.