A New Dolabrane-type Diterpene from Ceriops tagal

A New Dolabrane-type Diterpene from Ceriops tagal
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DOI:
10.1177/1934578x1000500103
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发表时间:
2010-01
影响因子:
1.8
通讯作者:
Xiao-Wei Ouyang;Xiachang Wang;Qing-xi Yue;L. Hu
Xiao-Wei Ouyang;Xiachang Wang;Qing-xi Yue;L. Hu
中科院分区:
医学4区
文献类型:
--
作者:
Xiao-Wei Ouyang;Xiachang Wang;Qing-xi Yue;L. Hu

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从红树林Ceriops tagal的地上部分分离得到一个新的dolabrane型二萜化合物,命名为tagalsin O 1,以及6个已知的类似物2-7。根据它们的光谱数据确定了它们的结构和相对构型。评价了分离的化合物对HeLa人宫颈癌细胞系的细胞毒性。
A new dolabrane-type diterpene named tagalsin O 1, together with six known analogues 2-7, were isolated from the aerial part of the mangrove plant Ceriops tagal. The structures and relative configurations were elucidated on the basis of their spectroscopic data. Cytotoxicity of the isolated compounds against HeLa human cervical carcinoma cancer cell line was evaluated.