Influence of motor complete spinal cord injury on visceral and subcutaneous adipose tissue measured by multi-axial magnetic resonance imaging
Influence of motor complete spinal cord injury on visceral and subcutaneous adipose tissue measured by multi-axial magnetic resonance imaging
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DOI：
10.1179/107902610x12911165975106
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发表时间：
2011-01-01
影响因子：
1.7
通讯作者：
Gater, David R.
中科院分区：
文献类型：
--
作者：
Gorgey, Ashraf S.;Mather, Kieren J.;Gater, David R.
目的：腹部肥胖与高水平的内脏脂肪组织（VAT）、皮下脂肪组织（SAT）以及VAT / SAT比例的增加有关，具有重大的健康风险。目的是确定脊髓损伤（SCI）对单轴横截面积（CSA）切片与多轴磁共振成像（MRI）上VAT和SAT的平均CSA或体积之间的关系的影响；以及与整个身体组成和人体测量学的关系。方法：13例健康男性外伤性运动完全性脊髓损伤患者采用快速自旋回声MRI测量多轴片VAT和SAT，然后采用双能x线吸收仪测量全身无脂质量（FFM）和脂肪质量（FM）。在坐姿时也测量腰围（WC）。结果：VAT和SAT主干csa分别为99 +/- 51和164 +/- 69 cm(2)， VAT与SAT之比为0.68 +/- 0.33。单片VAT和SAT的CSA可以很好地预测平均CSA，而对多轴片的体积预测则较为温和。增值税和SAT分别占总FM的5.7 +/- 1.8%和9.7 +/- 3.2%。体FFM百分比与VAT和SAT体积呈负相关，但与单轴CSA无关。结论：单片CSA可以适度预测脊髓损伤患者多轴片的体积，但与任何身体组成变量无关。增加的FFM百分比与跨多轴切片测量的VAT和SAT体积的减少有关。VAT / SAT比值大于0.4，提示SCI患者发生代谢后遗症的风险较高。
Objective: Abdominal obesity conveys substantial health risks, in association with high levels of visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT) and an increased proportion of VAT to SAT. The purposes were to determine the influence of spinal cord injury (SCI) on the associations between single axial cross-sectional area (CSA) slices and the average CSA or volumes of VAT and SAT across multi-axial slices of magnetic resonance imaging (MRI); and the relationships relative to the whole body composition and anthropometrics.Methods: Thirteen healthy male participants with traumatic motor complete SCI underwent fast spin-echo MRI to measure VAT and SAT across multi-axial slices, followed by dual-energy X-ray absorptiometry to measure whole body fat-free mass (FFM) and fat mass (FM). Waist circumference (WC) was also measured in the seated position.Results: The trunk CSAs of VAT and SAT were 99 +/- 51 and 164 +/- 69 cm(2), respectively, and the ratio of VAT to SAT was 0.68 +/- 0.33. The CSAs of VAT and SAT at a single slice strongly predicted the average CSA and modestly predicted the volumes across multi-axial slices. VAT and SAT represented 5.7 +/- 1.8% and 9.7 +/- 3.2% of the total body FM, respectively. Percent body FFM was negatively related to VAT and SAT volumes, but not to a single axial CSA.Conclusion: A single slice CSA can modestly predict the volume of multi-axial slices in individuals with SCI, yet it is not related to any of the body composition variables. Increased percent FFM is associated with a reduction in VAT and SAT volumes measured across multi-axial slices. The ratio of VAT to SAT is greater than 0.4, suggesting that individuals with SCI are at high risk of developing metabolic sequelae.