Hydrophilic PDMS microchannels for high-throughput formation of oil-in-water microdroplets and water-in-oil-in-water double emulsions
Hydrophilic PDMS microchannels for high-throughput formation of oil-in-water microdroplets and water-in-oil-in-water double emulsions
复制标题
DOI：
10.1039/c004046k
复制
发表时间：
2010-01-01
期刊：
影响因子：
6.1
通讯作者：
Huck, Wilhelm T. S.
中科院分区：
文献类型：
--
作者：
Bauer, Wolfgang-Andreas C.;Fischlechner, Martin;Huck, Wilhelm T. S.
在这里，我们提出了一种新的表面修饰方法，该方法基于PDMS微流控器件中产生亲水性微通道的聚电解质的顺序逐层沉积。这种涂层长期稳定，甚至在通道表面处理几个月后也能产生单分散的水包油微滴。由于聚电解质的坚固性，可以应用超高流速的多层膜，使得在喷射模式下形成高通量液滴成为可能。此外，我们成功地利用我们的方法对组装的微通道的某些区域的表面性质进行了选择性的修饰。由此产生的部分亲水、部分疏水的微流控装置允许生产单分散的水包油双乳液。
Here we present a novel surface modification method based on the sequential layer-by-layer deposition of polyelectrolytes yielding hydrophilic microchannels in PDMS-based microfluidic devices. The coatings are long-term stable and allow for the generation of monodisperse oil-in-water microdroplets even several months after the channel surface treatment. Due to the robustness of the polyelectrolyte multilayers ultra-high flow rates can be applied, making high-throughput droplet formation in the jetting mode possible. Furthermore, we successfully used our method to selectively modify the surface properties in certain areas of assembled microchannels. The resulting partially hydrophilic, partially hydrophobic microfluidic devices allow for the production of monodisperse water-in-oil-in-water double emulsions.