High fluorescence selectivity and visual detection of G-quadruplex structures by a novel dinuclear ruthenium complex.

High fluorescence selectivity and visual detection of G-quadruplex structures by a novel dinuclear ruthenium complex.
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DOI:
10.1039/b918045a
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发表时间:
2010-01
影响因子:
4.9
通讯作者:
Liang Xu;Dan Zhang;Jinguo Huang;Minggang Deng;Ming Zhang;Xiang Zhou
Liang Xu;Dan Zhang;Jinguo Huang;Minggang Deng;Ming Zhang;Xiang Zhou
中科院分区:
化学2区
文献类型:
--
作者:
Liang Xu;Dan Zhang;Jinguo Huang;Minggang Deng;Ming Zhang;Xiang Zhou

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生成了一种新型的双核钌(II)配合物,在DNA四联结构和双联结构之间具有很高的荧光选择性,并且利用碘化物猝灭策略,可以很容易地用肉眼区分g -四联结构和双联结构。
A novel dinuclear ruthenium(II) complex with high fluorescent selectivity between DNA quadruplex structures and duplex structures was generated, and using an iodide-quenching strategy, G-quadruplex structures can be easily distinguished from duplex structures by the naked eye.