Long-term corneal endothelial cell changes in pediatric intraocular lens reposition and exchange cases
Long-term corneal endothelial cell changes in pediatric intraocular lens reposition and exchange cases
复制标题
小儿人工晶状体复位和置换病例中的长期角膜内皮细胞变化
DOI：
10.1007/s00417-011-1837-z
复制
发表时间：
2012-04-01
影响因子：
2.7
通讯作者：
Liu, Yizhi
中科院分区：
文献类型：
--
作者：
Wang, Yan;Wu, Mingxing;Liu, Yizhi
PurposeTo evaluate long-term corneal endothelial cell changes of intraocular lens (IOL) reposition and exchange in children.SettingState key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, ChinaMethodsIn this retrospective study, all IOL reposition and exchange procedures performed in patients under 14 years old between January 1999 and April 2009 were included. Follow-up outcomes included corneal endothelial cell density, hexagonality, coefficient of variance, average cell size.ResultsIOL reposition procedures in 12 eyes (12 cases) (reposition group, RPG), and IOL exchanges in eight eyes (eight cases) (exchange group, EXG) were performed because of IOL pupillary capture or IOL dislocation. Median of follow-up was 44.5 months in RPG and 66.2 months in EXG. The density of corneal endothelial cells in RPG (2,053 ± 493/mm2) and EXG (2,100 ± 758/mm2) was significantly decreased in comparison to the control eyes (3,116 ± 335/mm2). Hexagonality of corneal endothelial cells and coefficient of variance showed no difference among the control group, RPG and EXG (P> 0.05).ConclusionsThe density of corneal endothelial cells was conspicuously decreased after IOL reposition or exchange procedures in childhood cases. Longer follow-up must be conducted in these cases.
