Low awareness of and willingness to use PrEP in the Chinese YMSM: An alert in YMSM HIV prevention
Low awareness of and willingness to use PrEP in the Chinese YMSM: An alert in YMSM HIV prevention
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DOI：
10.1111/hiv.12990
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发表时间：
2020-11-16
期刊：
影响因子：
3
通讯作者：
Ma, Jun
中科院分区：
文献类型：
--
作者：
Cui, Zhuang;Huang, Huijie;Ma, Jun
尽管中国年轻男男性行为者（YMSM）是开展暴露前预防（PrEP）的关键人群，但其使用PrEP的意识和意愿尚不清楚。我们报告了与人群中PrEP意识和意愿相关的因素。方法2018年8月1日至12月31日，对495名年龄在15-24岁的男性进行PrEP认知和使用意愿的横断面研究。使用Logistic回归模型确定与两项结果相关的因素：PrEP意识；结果在495名符合条件的参与者中，129名参与者（26.1%）了解PrEP，其中YMSM的PrEP知晓率与高等教育程度[调整比值比(aOR) = 1.812, 95% CI: 1.113-2.951]和既往HIV检测（aOR = 3.507, 95% CI: 1.261-9.752）相关。在当地居住时间较短（aOR = 0.317, 95% CI: 0.101 ~ 0.992）和通过网络寻找伴侣（aOR = 0.171, 95% CI: 0.096 ~ 0.305）的男青年对PrEP的知晓程度较低。在之前了解PrEP的人中，有36人（27.9%）表示愿意使用PrEP。PrEP意愿与网络性伴侣寻找相关（aOR = 9.593, 95% CI: 1.965 ~ 46.844）。影响那些知道PrEP但拒绝使用的主要障碍是PrEP的高价格（69.9%）、需要持续使用安全套（52.7%）、担心副作用（39.8%）和预防有效性（22.6%）。结论我国青年男性对PrEP的认知度和使用意愿较低，应加强PrEP的宣传，特别是通过网络和交友软件进行宣传。
Objectives Despite being a key population in whom to initiate pre-exposure prophylaxis (PrEP), the awareness of and willingness to use PrEP are still unclear in Chinese young men who have sex with men (YMSM). We report factors associated with PrEP awareness and willingness in the population.Methods From 1 August to 31 December 2018, 495 participants aged 15-24 years were included in a cross-sectional study about awareness of and willingness to use PrEP among YMSM. Logistic regression models were used to identify factors associated with two outcomes: awareness of PrEP; and willingness to use PrEP.Results Among 495 eligible participants, 129 participants (26.1%) knew about PrEP. PrEP awareness among YMSM was associated with higher education level [adjusted odds ratio (aOR) = 1.812, 95% CI: 1.113-2.951] and previous HIV testing (aOR = 3.507, 95% CI: 1.261-9.752). YMSM with shorter local residence time (aOR = 0.317, 95% CI: 0.101-0.992) and internet-based partner-seeking (aOR = 0.171, 95% CI: 0.096-0.305) were less likely to be aware of PrEP. In those with previous knowledge of PrEP, 36 (27.9%) conveyed their willingness to use it. PrEP willingness was associated with internet-based partner-seeking (aOR = 9.593, 95% CI: 1.965-46.844). The main barriers influencing those who knew about PrEP but refused to use it were the high price of PrEP (69.9%), the need to use condoms consistently (52.7%), and concerns about side effects (39.8%) and effectiveness of prevention (22.6%).Conclusions Chinese YMSM have low awareness of and willingness to use PrEP. Adequate PrEP promotions should be implemented, especially on the Internet and dating software.