The Symptoms of unstable angina - Do women and men differ?
The Symptoms of unstable angina - Do women and men differ?
复制标题
DOI：
10.1097/00006199-200303000-00007
复制
发表时间：
2003-03-01
期刊：
影响因子：
2.5
通讯作者：
Zerwic, JJ
中科院分区：
文献类型：
--
作者：
DeVon, HA;Zerwic, JJ
背景。研究表明，女性和男性在冠心病的流行病学、表现和结局方面存在差异。 目的：本研究的目的是确定不稳定型心绞痛 (UA) 的症状是否存在性别差异，如果存在，则确定在控制年龄、糖尿病、焦虑、抑郁和功能状态后这些差异是否仍然存在。 方法。这项描述性研究采用非实验性定量设计，从城市和郊区医疗中心招募了 50 名因 UA 住院的女性和 50 名男性的方便样本。工具包括不稳定心绞痛症状问卷 (UASQ)、医院焦虑和抑郁量表 (HADS) 以及加拿大心血管学会 (CCS) 心绞痛分类。 结果：多变量分析表明，女性明显 (p < .05) 出现更多的呼吸短促（74% vs. 60%）、虚弱（74% vs. 48%）、呼吸困难（66% vs. 48%）。 38%）、恶心（42% vs. 22%）和食欲不振（40% vs. 10%）均高于男性。在控制了年龄、糖尿病、焦虑、抑郁和功能状态后，女性仍然比男性更容易出现虚弱 (p = .03)、呼吸困难 (p = .02)、恶心 (p = .03) 和食欲不振 (p = .02)。症状描述符的卡方分析显示，女性更多地表现出上背痛（42% vs. 18%）、刺痛（32% vs. 12%）和刀割样疼痛（28% vs. 12%）（p < .05）。女性的抑郁症发病率也显着较高（22% vs. 2%，p < .01）。结论：研究结果表明，女性和男性在 UA 发作期间有相似的症状，但是，较高比例的女性症状不太典型。
Background. Research has shown that there are differences between women and men in the epidemiology, presentation, and outcomes of coronary heart disease.Objectives: The purpose of this study was to determine if there were sex differences in the symptoms of unstable angina (UA) and if so, to determine if these differences remained after controlling for age, diabetes, anxiety, depression, and functional status.Method. This descriptive study used a nonexperimental, quantitative design, A convenience sample of 50 women and 50 men, hospitalized with UA, were recruited from an urban and a suburban medical center. Instruments included the Unstable Angina Symptoms Questionnaire (UASQ), the Hospital Anxiety and Depression Scale (HADS), and the Canadian Cardiovascular Society (CCS) classification of angina.Results: Multivariate analysis indicated that women experienced significantly (p < .05) more shortness of breath (74% vs. 60%), weakness (74% vs. 48%), difficulty breathing (66% vs. 38%), nausea (42% vs. 22%), and loss of appetite (40% vs. 10%) than men. After controlling for age, diabetes, anxiety, depression, and functional status, women were still more likely than men to report weakness (p = .03), difficulty breathing (p = .02), nausea (p = .03), and loss of appetite (p = .02). Chi-square analysis of symptom descriptors revealed that women disclosed more (p < .05) upper back pain (42% vs. 18%), stabbing pain (32% vs. 12%), and knifelike pain (28% vs. 12%). Women also had a significantly higher incidence of depression (22% vs. 2%, p < .01).Conclusions: Findings suggest that women and men have similar symptoms during an episode of UA, however, a higher proportion of women have less typical symptoms.