Backbone resonance assignments of the 48 kDa dimeric putative 18S rRNA-methyltransferase Nep1 from Methanocaldococcus jannaschii.
Backbone resonance assignments of the 48 kDa dimeric putative 18S rRNA-methyltransferase Nep1 from Methanocaldococcus jannaschii.
复制标题
来自詹纳斯基甲烷球菌的 48 kDa 二聚体推定 18S rRNA-甲基转移酶 Nep1 的主链共振分配。
DOI：
10.1007/s12104-009-9187-z
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发表时间：
2009
影响因子：
0.9
通讯作者：
Wöhnert,Jens
中科院分区：
文献类型：
--
作者：
Wurm,JanPhilip;Duchardt,Elke;Meyer,Britta;Leal,BelindaZ;Kötter,Peter;Entian,Karl-Dieter;Wöhnert,Jens
来自詹氏甲烷球菌的Nep 1是属于S-腺苷甲硫氨酸依赖性RNA-甲基转移酶的SPOUT类的48 kDa二聚体蛋白，并且充当核糖体装配因子。人类同源基因的突变是Bowen-Conradi综合征的原因。我们在此报告1H，15 N和13 C化学位移分配的蛋白质在其载脂蛋白状态的骨干。
Nep1 fromMethanocaldococcus jannaschiiis a 48 kDa dimeric protein belonging to the SPOUT-class of S-adenosylmethionine dependent RNA-methyltransferases and acting as a ribosome assembly factor. Mutations in the human homolog are the cause of Bowen-Conradi syndrome. We report here1H,15N and13C chemical shift assignments for the backbone of the protein in its apo state.