Cardiac autonomic hypofunction in preschool children with short nocturnal sleep
Cardiac autonomic hypofunction in preschool children with short nocturnal sleep
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DOI：
10.1620/tjem.208.235
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发表时间：
2006-03-01
影响因子：
2.2
通讯作者：
Wood, DC
中科院分区：
文献类型：
--
作者：
Sampei, M;Murata, K;Wood, DC
睡眠不足的学龄前儿童可能会出现自主神经症状或低血压。心率变异性，反映心脏副交感神经和交感神经活动，和血压进行了评估，以澄清夜间睡眠时间对心脏自主神经功能的影响，在134名5和6岁的学龄前儿童。父母报告了他们孩子平日的典型就寝时间和起床时间。在儿童中，平均夜间睡眠时间（标准差）为575 +/- 42分钟。副交感神经和交感神经活动和收缩压（SBP）显着较低的80名儿童与睡眠时间短（夜间睡眠时间= 10小时）。在儿童中，只有收缩压与夜间睡眠时间呈正相关（p < 0.001）;而且，经多元logistic回归分析判断，夜间睡眠时间短与低血压（收缩压< 100 mmHg）显著相关。在儿童中，副交感神经活性与收缩压呈负相关，交感神经活性与舒张压呈负相关（p < 0.05）。这些发现表明，夜间睡眠缩短与学龄前儿童心脏自主神经功能减退和低收缩压有关。我们认为睡眠时间是儿童自主神经发育的重要预测因素。
Preschool children with sleep deficit may suffer from autonomic symptoms or hypotension. Heart rate variability, reflecting cardiac parasympathetic and sympathetic activities, and blood pressure were assessed to clarify the effects of nocturnal sleep duration on cardiac autonomic function in 134 preschool children aged 5 and 6 years. Parents reported their children's typical bedtimes and wake times for weekdays. In the children, the mean nocturnal sleep duration (standard deviation) was 575 +/- 42 min. The parasympathetic and sympathetic activities and systolic blood pressure (SBP) were significantly lower in the 80 children with short sleep (nocturnal sleep duration = 10 hrs). Only the SBP was positively correlated with nocturnal sleep duration in the children (p < 0.001); also, short nocturnal sleep duration was significantly related to hypotension (SBP < 100 mmHg), as judged by multiple logistic regression analysis. Among the children, inverse correlations were seen between the parasympathetic activity and SBP and between the sympathetic activity and diastolic blood pressure (p < 0.05). These findings indicate that shortening of nocturnal sleep is associated with cardiac autonomic hypofunction and low SBP in preschool children. We suggest that sleep duration is an important predictor for autonomic development in childhood.