PONTINE TASTE AREA IN RAT
PONTINE TASTE AREA IN RAT
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DOI：
10.1016/0006-8993(75)90469-2
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发表时间：
1975-01-01
期刊：
影响因子：
2.9
通讯作者：
PFAFFMANN, C
中科院分区：
文献类型：
--
作者：
NORGREN, R;PFAFFMANN, C
脑桥味觉区将味觉信息从孤核的喙极传递到丘脑和腹侧前脑。该区域的电生理学研究分三个阶段进行。首先，使用施加到前舌的有味、热和触觉刺激来绘制来自脑桥背侧的多单位反应。当臂结膜从小脑进入脑桥时，味觉区位于结膜臂的背侧和腹侧。其次，味觉刺激被独立地施加到前舌和后舌，以确定两个区域的受体是否在脑桥中出现。与从舌咽神经获得的特征相似的反应位于脑桥味觉区的背侧边缘。在更腹侧，来自后舌的反应模仿了前舌反应，但其幅度小于发生在味觉区腹侧边缘的最大前反应。第三，在脑桥背侧分离出71个单个单元，并分别测试前舌和后舌的味觉刺激敏感性。超过一半的单位对味觉刺激做出反应——有些仅来自前舌，有些仅来自后舌，但大多数对施加到任一区域的刺激都有反应。在后一种情况下，测试的 10 个单元中有 7 个在用赛洛卡因注入中耳麻醉鼓索后继续做出反应，从而证明了真正的舌咽输入。这证明来自两个不同感受野的味觉信息可能会聚在同一个中枢神经元上。
The pontine taste area relays gustatory information from the rostral pole of the solitary nucleus to both the thalamus and ventral forebrain. An electrophysiological investigation of this area was carried out in 3 stages. First, multiunit responses from the dorsal pons were mapped using sapid, thermal, and tactile stimuli applied to the anterior tongue. The gustatory zone lies within and just dorsal and ventral to the brachium conjunctivum as it enters the pons from the cerebellum. Second, gustatory stimuli were applied independently to the anterior and posterior tongue to determine whether receptors in both fields are represented in the pons. Responses with characteristics similar to those obtained from the glossopharyngeal nerve were located on the dorsal edge of the pontine gustatory zone. More ventrally the responses from the posterior tongue mimicked anterior tongue responses, but were of lesser amplitude than the largest anterior responses occurring at the ventral edge of the gustatory zone. Third, 71 single units were isolated in the dorsal pons, and tested for sensitivity to gustatory stimulation of the anterior and posterior tongue separately. More than half the units responded to gustatory stimuli—some from the anterior tongue alone, some from the posterior alone but most responded to stimuli applied to either field. In the latter instance 7 of 10 units tested continued to respond after anesthetizing the chorda tympani with Xylocaine instilled into the middle ear, thus demonstrating a true glossopharyngeal input. This proves that gustatory information from two distinct receptive fields may converge on the same central neuron.