Years of plutonium exposure to the Manhattan Project plutonium workers: An update

Years of plutonium exposure to the Manhattan Project plutonium workers: An update
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DOI:
10.1097/00004032-199710000-00004
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发表时间:
1997-10-01
期刊:
影响因子:
2.2
通讯作者:
Johnson, ER
Johnson, ER
中科院分区:
医学4区
文献类型:
--
作者:
Voelz, GL;Lawrence, JNP;Johnson, ER

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在过去50年中,对在洛斯阿拉莫斯从事最初钚研究和开发工作的26名白人工作人员进行了定期检查,以确定内部钚沉积可能对健康产生的影响,其有效剂量范围为0.1至7.2西沃特,中位数为1.25西沃特,截至1994年底,已有7人死亡,而根据美国白人男性在一般人口中的死亡率,预计死亡人数为16人。标准化死亡率(SMR)为0.43,与同期未暴露的876名洛斯阿拉莫斯工作人员相比,钚工作人员的死亡率也没有升高(SMR = 0.77)。这19人患有男性人口的疾病和身体变化,平均年龄为72岁(范围= 69岁至86岁)。26名工人中有8人被诊断出患有一种或多种癌症,这在预期范围内。7名死者中有3人的根本死因是癌症,即前列腺癌、肺癌和骨癌。所有癌症的死亡率在统计上没有升高。将钚对这些人的有效剂量与目前的辐射防护指南进行比较。
Twenty-six white mate workers who did the original plutonium research and development work at Los Alamos have been examined periodically over the past 50 y to identify possible health effects from internal plutonium depositions, Their effective doses range from 0.1 to 7.2 Sv with a median value of 1.25 Sv, As of the end of 1994, 7 individuals have died compared with an expected 16 deaths based on mortality rates of U.S. white males in the general population. The standardized mortality ratio (SMR) is 0.43, When compared with 876 unexposed Los Alamos workers of the same period, the plutonium worker's mortality rate was also not elevated (SMR = 0.77). The 19 living persons have diseases and physical changes characteristic of a male population with a median age of 72 y (range = 69 to 86 y). Eight of the twenty-six workers have been diagnosed as having one or more cancers, which is within the expected range. The underlying cause of death in three of the seven deceased persons was from cancer, namely cancer of prostate, lung, and bone. Mortality from all cancers was not statistically elevated. The effective doses from plutonium to these individuals are compared with current radiation protection guidelines.