DEVELOPMENTAL GRADIENTS IN THE EMBRYONIC CHICKS BASILAR PAPILLA
DEVELOPMENTAL GRADIENTS IN THE EMBRYONIC CHICKS BASILAR PAPILLA
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DOI：
10.3109/00016488409130963
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发表时间：
1984-01-01
影响因子：
1.4
通讯作者：
COHEN, GM
中科院分区：
文献类型：
--
作者：
FERMIN, CD;COHEN, GM
对鸡胚（Gallus arthriticus）从31期到46期（孵化期）的基底乳头进行了细胞学检查。通过使用光学显微镜分析沿着整个lagenar长度的连续切片（1-5 μ M）和EM检查来自近端、中间和远端区域的代表性薄切片来制备发育重建物。确定了两个梯度，横向和纵向。在纵向梯度，midbasal基底乳头，直接位于上述的平衡听神经节，发达国家的近端和远端地区的毛细胞和传入突触的成熟证明。在横向梯度中，高毛细胞和传入突触先于短毛细胞和它们各自的传入终末发育。传出突触发生遵循相同的2个梯度，比传入晚几天。传入突触发生与外淋巴间隙的开放和盖膜的完成相对应。
The basilar papilla, the avian counterpart of Corti''s organ, was examined cytologically in the embryonic chick (Gallus domesticus) from stages 31 through 46 (hatching). Developmental reconstructions were prepared by using light microscopy to analyze serial sections (1-5 .mu.M) along the entire lagenar length and EM to examine representative thin sections from the proximal, medial and distal regions. Two gradients were identified, the lateral and longitudinal. In the longitudinal gradient, the midbasal basilar papilla, which lies directly above the statoacoustic ganglion, develops before the proximal and distal regions as evidenced by the maturation of hair cells and afferent synapses. In the lateral gradient, tall hair cells and afferent synapses develop before short hair cells and their respective afferent terminals. Efferent synaptogenesis follows the same 2 gradients several days later than the afferents. Afferent synaptogenesis corresponds with the opening of the perilymphatic spaces and completion of the tectorial membrane.