The effects of smoking on myocardial conduction in the human heart.
The effects of smoking on myocardial conduction in the human heart.
复制标题
吸烟对人体心脏心肌传导的影响。
DOI：
10.1016/s0002-8703(76)80536-4
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发表时间：
1976
影响因子：
4.8
通讯作者：
E. Fletcher
中科院分区：
文献类型：
--
作者：
S. Bekheit;E. Fletcher
吸几口烟会增加传导速度，缩短房室结的有效不应期。这些作用归因于吸收的微量尼古丁产生的肾上腺素能刺激。无论是由心房起搏引起的还是自发发生的文氏阻滞都被消除。希氏-浦肯野系统和预激综合征异常通路的传导速度不受影响。吸烟增加心房颤动的心室率，并拮抗洋地黄的胆碱能作用。
Inhalation of a few puffs on a cigarette increases the velocity of conduction and shortens the effective refractory period of the A-V node. These effects are attributed to adrenergic stimulation produced by minute amounts of nicotine absorbed. Wenckebach block is abolished whether induced by atrial pacing or occurring spontaneously. Conduction velocity in the His-Purkinje system and in the anomalous pathways in the WPW syndrome were not affected. Smoking increases the ventricular rate in atrial fibrillation, and antagonizes the cholinergic effects of digitalis.