Does erotic stimulus presentation design affect brain activation patterns?: Event-related vs. blocked fMRI designs
Does erotic stimulus presentation design affect brain activation patterns?: Event-related vs. blocked fMRI designs
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DOI：
10.1186/1744-9081-4-30
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发表时间：
2008-07-22
影响因子：
5.1
通讯作者：
Smolka, Michael N.
中科院分区：
文献类型：
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作者：
Buehler, Mira;Vollstaedt-Klein, Sabine;Smolka, Michael N.
背景资料：现有的脑成像研究，调查性唤起通过介绍色情图片或电影摘录，主要是使用阻塞设计与长刺激presentation times.Methods：为了阐明实验功能磁共振成像（fMRI）设计如何影响刺激诱导的大脑活动，我们比较了简短的事件相关的介绍色情与中性刺激与阻塞呈现10名男性志愿者。结果：大脑激活根据设计类型不同，只有10%的体素显示任务相关的大脑活动。阻断和事件相关刺激呈现的差异在枕颞区和颞区被发现（Brodmann区（BA）19、37、48），顶叶区（BA 7，40）和额叶区域（BA 6，44）结论：我们的研究结果表明-当核心兴趣是检测与色情刺激的即时处理相关联的网络时，相关设计可能是潜在的替代方案。此外，与事件相关的刺激呈现相比，阻断的刺激呈现允许出现和检测非特异性的次级过程，例如持续注意力、运动想象和性唤起抑制。
Background: Existing brain imaging studies, investigating sexual arousal via the presentation of erotic pictures or film excerpts, have mainly used blocked designs with long stimulus presentation times.Methods: To clarify how experimental functional magnetic resonance imaging (fMRI) design affects stimulus-induced brain activity, we compared brief event-related presentation of erotic vs. neutral stimuli with blocked presentation in 10 male volunteers.Results: Brain activation differed depending on design type in only 10% of the voxels showing task related brain activity. Differences between blocked and event-related stimulus presentation were found in occipitotemporal and temporal regions (Brodmann Area (BA) 19, 37, 48), parietal areas (BA 7, 40) and areas in the frontal lobe (BA 6, 44).Conclusion: Our results suggest that event-related designs might be a potential alternative when the core interest is the detection of networks associated with immediate processing of erotic stimuli. Additionally, blocked, compared to event-related, stimulus presentation allows the emergence and detection of non-specific secondary processes, such as sustained attention, motor imagery and inhibition of sexual arousal.