Quality of life in older people with oral cancer
Quality of life in older people with oral cancer
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DOI：
10.1016/j.bjoms.2012.01.010
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发表时间：
2012-12-01
影响因子：
1.8
通讯作者：
Rogers, S. N.
中科院分区：
文献类型：
--
作者：
Laraway, D. C.;Lakshmiah, R.;Rogers, S. N.
有越来越多的老年人口患有口腔癌，并存活下来。关于治疗的决定很复杂，而且在一定程度上受到健康相关生活质量(HRQOL)的预后和预期结果的影响。我们使用华盛顿大学头颈生活质量量表(UWQOL)来比较不同年龄组患者在初次手术后最接近一年的时间的HRQL。存活率是使用国家统计局的数据进行分析的。主要分析包括1992至2009年间在安特里大学医院区域颌面部单元连续治疗的1091例口腔鳞状细胞癌(SCC)患者。638名患者的UWQOL数据从治疗后大约一年开始可用。与接受手术治疗的年轻头颈癌患者相比，年龄较大的患者(65岁或以上)在外表、言语、唾液(75岁及以上)、疼痛、肩部、情绪和焦虑方面表现出更好的身体和情绪功能。总而言之，老年患者似乎很好地应对和适应治疗，这反映在他们的HRQOL评分上，他们在许多领域比年轻的头颈癌患者更高。(C)2012年英国口腔颌面外科医生协会。爱思唯尔有限公司出版。保留所有权利。
There is a growing elderly population presenting with, and surviving, oral cancer. Making decisions about treatment is complex, and is influenced in part by prognosis and expected outcomes for health-related quality of life (HRQoL). We used the University of Washington Head and Neck Quality of Life scale (UWQoL) to compare HRQoL in patients by age group at a time closest to one year after primary surgery. Survival was analysed using data from the Office for National Statistics. A consecutive series of 1091 patients treated curatively for oral squamous cell carcinoma (SCC) at the regional maxillofacial unit at Aintree University Hospital between 1992 and 2009 were included in the main analysis. UWQoL data for 638 patients were available from about one year after treatment. Older patients (65 years or over) reported better physical and emotional function notably in regard to appearance, speech, saliva (75 years and over), pain, shoulder, mood, and anxiety than younger patients with head and neck cancer treated by operation. In conclusion, older patients seem to cope and adjust well to treatment and this is reflected in their HRQoL scores, which are higher in many domains than those of younger patients with head and neck cancer. (C) 2012 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.